Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
Jun. 30, 2019	Jun. 30, 2018
Operating Activities:
Net loss	$ (72,559)	$ (36,827)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:
Depreciation and amortization	1,583	1,207
Amortization of discount on marketable securities	(2,455)	(1,656)
Gain on free shares	(551)	0
Stock-based compensation	9,390	6,564
Net loss on lease termination	218	0
Other	11	465
Net changes in operating assets and liabilities:
Interest receivable	(391)	(322)
Accounts receivable	(7,422)	(1,634)
Prepaid expenses and other assets	(5,449)	(3,564)
Operating lease right-of-use assets	1,923	0
Accounts payable and accrued liabilities	1,811	2,733
Accrued compensation and employee benefits	(764)	(1,133)
Deferred revenues	(10,821)	138,474
Long-term portion of lease liabilities	(563)	0
Other non-current liabilities	1,327	0
Net cash (used in) provided by operating activities	(84,712)	104,307
Investing Activities:
Purchases of marketable securities	(244,306)	(451,240)
Maturities of marketable securities	226,884	133,297
Purchases of property and equipment	(9,760)	(5,768)
Net cash used in investing activities	(27,182)	(323,711)
Financing Activities:
Proceeds from public offering of common stock, net of issuance costs	136,308	215,756
Taxes paid related to net share settlement of equity awards	(296)	(57)
Proceeds from issuance of common stock	4,094	13,285
Net cash provided by financing activities	140,106	228,984
Effects of changes in foreign exchange rates	592	0
Net increase in cash, cash equivalents, and restricted cash	28,804	9,580
Cash, cash equivalents, and restricted cash, beginning of period	143,918	53,326
Cash, cash equivalents, and restricted cash, end of period	172,722	62,906
Supplemental disclosure of non-cash activities:
Property and equipment included in accrued liabilities	1,679	1,836
Right-of-use assets obtained in exchange for lease obligations	$ 29,671	$ 0

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Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration