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Cash and Marketable Securities - Summary of Cash Equivalents and Available-for-Sale Securities (Detail) - USD ($) $ in Thousands	Sep. 30, 2019	Dec. 31, 2018	Sep. 30, 2018	Dec. 31, 2017
ASSETS
Cash equivalents, Amortized Cost	$ 114,291	$ 140,418	$ 39,298	$ 49,826
Available-for-sale securities, Amortized Cost	292,931	259,974
Available-for-sale securities, Gross Unrealized Gains	421	0
Available-for-sale securities, Gross Unrealized (Losses)	(2)	(259)
Available-for-sale securities, Estimated Fair Value	293,350	259,715
Total cash equivalents and available-for-sale securities, Amortized Cost	370,144	363,265
Total cash equivalents and available-for-sale securities, Gross Unrealized Gains	421	0
Total cash equivalents and available-for-sale securities, Gross Unrealized (Losses)	(2)	(259)
Total cash equivalents and available-for-sale securities, Estimated Fair Value	370,563	363,006
Money market funds
ASSETS
Cash equivalents, Amortized Cost	77,213	103,291
Cash equivalents, Gross Unrealized Gains	0	0
Cash equivalents, Gross Unrealized (Losses)	0	0
Cash equivalents, Estimated Fair Value	77,213	103,291
Cash equivalents
ASSETS
Cash equivalents, Amortized Cost	77,213	103,291
Cash equivalents, Gross Unrealized Gains	0	0
Cash equivalents, Gross Unrealized (Losses)	0	0
Cash equivalents, Estimated Fair Value	77,213	103,291
Commercial paper securities
ASSETS
Available-for-sale securities, Amortized Cost	180,590	177,353
Available-for-sale securities, Gross Unrealized Gains	224	0
Available-for-sale securities, Gross Unrealized (Losses)	(2)	(129)
Available-for-sale securities, Estimated Fair Value	180,812	177,224
Corporate debt securities
ASSETS
Available-for-sale securities, Amortized Cost	70,947	63,981
Available-for-sale securities, Gross Unrealized Gains	167	0
Available-for-sale securities, Gross Unrealized (Losses)	0	(111)
Available-for-sale securities, Estimated Fair Value	71,114	63,870
U.S. government-sponsored entity debt securities
ASSETS
Available-for-sale securities, Amortized Cost	41,394	18,640
Available-for-sale securities, Gross Unrealized Gains	30	0
Available-for-sale securities, Gross Unrealized (Losses)	0	(19)
Available-for-sale securities, Estimated Fair Value	$ 41,424	$ 18,621

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