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Commitments and Contingencies - Additional Information (Detail)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2019
USD ($)
ft²
Mar. 31, 2019
Sep. 30, 2019
USD ($)
ft²
contract
Jun. 30, 2019
ft²
Jan. 31, 2019
ft²
Commitments And Contingencies [Line Items]          
Operating lease costs | $ $ 2.6   $ 5.3    
Lease option to extend     true    
Variable lease expense | $ $ 0.6   $ 1.2    
Cash paid for operating lease liabilities included net cash used in operating activities | $     $ 2.0    
Operating lease, weighted-average remaining lease term 9 years 1 month 6 days   9 years 1 month 6 days    
Operating lease, weighted-average discount rate 6.90%   6.90%    
Richmond Lease | Office and Laboratory          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft) 37,900   37,900    
Richmond Lease | Operating Lease One | Research and Office Space          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft) 7,700   7,700    
Lease expiration date     Aug. 31, 2019    
Valbonne Lease          
Commitments And Contingencies [Line Items]          
Additional property available under lease | contract     2    
Valbonne Lease | Operating Lease One | Research and Office Space          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft) 14,036   14,036    
Valbonne Lease | Operating Lease Two | Office Space          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft) 6,800   6,800    
Lease commencement date   Apr. 01, 2019      
Richmond and Valbonne Leases          
Commitments And Contingencies [Line Items]          
Lease option to extend     Certain of these leases also include renewal options at the election of the Company to renew or extend the lease for an additional five to ten years.    
Richmond and Valbonne Leases | Minimum          
Commitments And Contingencies [Line Items]          
Lease agreement, extendable lease term 5 years   5 years    
Richmond and Valbonne Leases | Maximum          
Commitments And Contingencies [Line Items]          
Lease agreement, extendable lease term 10 years   10 years    
Brisbane Lease          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft)       52,620  
Expected lease commencement period     2019-06    
Tenant improvement allowance | $ $ 6.8   $ 6.8    
Lease not yet commenced, tenant improvement allowance | $ $ 10.2   $ 10.2    
Brisbane Lease | Office and Laboratory          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft) 87,700   87,700    
Brisbane Lease | Office Space          
Commitments And Contingencies [Line Items]          
Area of space leased (in sqft)         35,080
Lease commencement period     2019-01