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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Operating Activities:    
Net loss $ (99,920) $ (49,670)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:    
Depreciation and amortization 2,742 1,668
Amortization of discount on marketable securities (3,715) (4,043)
Gain on free shares (488) 0
Stock-based compensation 14,091 10,374
Net loss on lease termination 218 0
Other (29) 715
Net changes in operating assets and liabilities:    
Interest receivable (305) (443)
Accounts receivable (17,280) (2,225)
Prepaid expenses and other assets (4,734) (1,851)
Operating lease right-of-use assets 3,796 0
Accounts payable and accrued liabilities (1,753) 789
Accrued compensation and employee benefits 1,608 1,127
Deferred revenues (20,477) 118,540
Long-term portion of lease liabilities (920) 0
Other non-current liabilities 3,580 1,730
Net cash (used in) provided by operating activities (123,586) 76,711
Investing Activities:    
Purchases of marketable securities (321,390) (451,239)
Maturities of marketable securities 292,147 230,547
Purchases of property and equipment (13,894) (15,028)
Purchase of additional Sangamo France shares (262) 0
Other investment 0 (5,221)
Net cash used in investing activities (43,399) (240,941)
Financing Activities:    
Proceeds from public offering of common stock, net of issuance costs 136,308 215,757
Taxes paid related to net share settlement of equity awards (388) (83)
Proceeds from issuance of common stock 4,890 14,469
Net cash provided by financing activities 140,810 230,143
Effects of changes in foreign exchange rates 48 0
Net (decrease) increase in cash, cash equivalents, and restricted cash (26,127) 65,913
Cash, cash equivalents, and restricted cash, beginning of period 143,918 53,326
Cash, cash equivalents, and restricted cash, end of period 117,791 119,239
Supplemental disclosure of non-cash activities:    
Property and equipment included in unpaid liabilities 4,257 5,813
Right-of-use assets obtained in exchange for lease obligations $ 29,647 $ 0