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Income Taxes - Additional Information (Detail) - USD ($) | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Income Taxes [Line Items] |  |  |
Increase (decrease) in deferred tax assets valuation allowance | $ (26,600,000) | $ (29,600,000) | $ (45,300,000)
Deferred tax assets, net operating loss carryforwards for federal | 622,600,000 |  |
Deferred tax assets, net operating loss carryforwards for state | 261,700,000 |  |
Federal research tax credit carryforwards | 21,900,000 |  |
State research tax credit carryforwards | 18,300,000 |  |
Accrued interest and/or penalties | 0 |  |
French |  |  |
Income Taxes [Line Items] |  |  |
Deferred tax assets, net operating loss carryforwards for foreign | $ 145,900,000 |  |

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