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Organization and Summary of Significant Accounting Policies - Revenues from Strategic Partnering Collaboration Agreements and Research Activity Grants (Detail) - Revenue from Contract with Customer - Revenue From Collaboration Agreements, Grants And Licensing Concentration Risk
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Pfizer      
Concentration Risk [Line Items]      
Percentage of revenues 40.00% 40.00% 47.00%
Biogen MA Inc      
Concentration Risk [Line Items]      
Percentage of revenues 24.00% 0.00% 0.00%
Kite Pharma, Inc. ("Kite")      
Concentration Risk [Line Items]      
Percentage of revenues 24.00% 34.00% 30.00%
Novartis Institutes For Bio Medical Research Inc      
Concentration Risk [Line Items]      
Percentage of revenues 4.00% 0.00% 0.00%
Sanofi      
Concentration Risk [Line Items]      
Percentage of revenues 5.00% 22.00% 16.00%