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Cash Equivalents and Marketable Securities - Summary of Cash Equivalents and Available-for-Sale Securities (Detail) - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Debt Securities, Available-for-sale [Line Items]
Cash and cash equivalents, at carrying value, total	$ 131,329	$ 80,428
Available-for-sale securities, amortized cost	560,575	303,546
Available-for-sale securities, gross unrealized gains	86	351
Available-for-sale securities, gross unrealized (Losses)	(37)	(19)
Available-for-sale securities, estimated fair value	560,624	303,878
Total cash equivalents and available-for-sale securities, amortized cost	613,740	337,040
Total cash equivalents and available-for-sale securities, gross unrealized gains	86	352
Total cash equivalents and available-for-sale securities, gross unrealized (losses)	(37)	(19)
Total cash equivalents and available-for-sale securities, estimated fair value	613,789	337,373
Money market funds
Debt Securities, Available-for-sale [Line Items]
Cash and cash equivalents, at carrying value, total	53,165	30,496
Cash equivalents, gross unrealized gains	0	0
Cash and cash equivalents accumulated gross unrealized loss before tax	0	0
Cash equivalents, estimated fair value	53,165	30,496
Commercial paper
Debt Securities, Available-for-sale [Line Items]
Cash and cash equivalents, at carrying value, total		2,998
Cash equivalents, gross unrealized gains		1
Cash and cash equivalents accumulated gross unrealized loss before tax		0
Cash equivalents, estimated fair value		2,999
Available-for-sale securities, amortized cost	213,500	155,230
Available-for-sale securities, gross unrealized gains	41	145
Available-for-sale securities, gross unrealized (Losses)	(8)	(7)
Available-for-sale securities, estimated fair value	213,533	155,368
Cash equivalents:
Debt Securities, Available-for-sale [Line Items]
Cash and cash equivalents, at carrying value, total	53,165	33,494
Cash equivalents, gross unrealized gains	0	1
Cash and cash equivalents accumulated gross unrealized loss before tax	0	0
Cash equivalents, estimated fair value	53,165	33,495
Corporate debt securities
Debt Securities, Available-for-sale [Line Items]
Available-for-sale securities, amortized cost	59,575	94,905
Available-for-sale securities, gross unrealized gains	16	115
Available-for-sale securities, gross unrealized (Losses)	(17)	(3)
Available-for-sale securities, estimated fair value	59,574	95,017
Certificates of deposit
Debt Securities, Available-for-sale [Line Items]
Available-for-sale securities, amortized cost	12,311
Available-for-sale securities, gross unrealized gains	0
Available-for-sale securities, gross unrealized (Losses)	0
Available-for-sale securities, estimated fair value	12,311
U.S. government-sponsored entity debt securities
Debt Securities, Available-for-sale [Line Items]
Available-for-sale securities, amortized cost	257,284	53,411
Available-for-sale securities, gross unrealized gains	19	91
Available-for-sale securities, gross unrealized (Losses)	(5)	(9)
Available-for-sale securities, estimated fair value	257,298	$ 53,493
Asset-backed securities
Debt Securities, Available-for-sale [Line Items]
Available-for-sale securities, amortized cost	17,905
Available-for-sale securities, gross unrealized gains	10
Available-for-sale securities, gross unrealized (Losses)	(7)
Available-for-sale securities, estimated fair value	$ 17,908

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