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Income Taxes - Schedule of Difference Between Benefit for Income Taxes and Federal Statutory Income Tax Rate (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Income Tax Disclosure [Abstract]
Tax at federal statutory rate	$ (25,363)	$ (20,038)	$ (14,467)
State taxes, net	(3,168)	(9,597)	(2,849)
Foreign rate differential	376	(665)	(177)
Global Intangible Low-Taxed Income	1,335	0	0
Non-deductible stock-based compensation	4,232	2,817	(2,729)
Research credits	(3,657)	(3,429)	(1,005)
Change in valuation allowance	26,537	29,655	20,271
Other	53	1,257	956
Income tax expense	$ 345	$ 0	$ 0

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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