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ORGANIZATION, BASIS OF PRESENTATION, AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Additional Information (Detail) - USD ($)
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 27,872,000 $ 21,553,000 $ 54,152,000 $ 34,629,000
Net loss $ (47,174,000) $ (35,965,000) $ (93,113,000) $ (78,939,000)
Earnings per share, basic (in dollars per share) $ (0.33) $ (0.26) $ (0.65) $ (0.62)
Impairment of goodwill or indefinite-lived intangible assets     $ 0  
Impairment of long-lived assets     0  
Letter of credit established as a deposit $ 1,500,000   1,500,000  
Pfizer SB-525        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 0   $ 0  
Pfizer SB-525 | Change in collaboration agreement scope | Collaboration agreement        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues       $ 3,100,000
Net loss       $ 3,100,000
Earnings per share, basic (in dollars per share)       $ 0.02