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ORGANIZATION, BASIS OF PRESENTATION, AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Additional Information (Detail) - USD ($) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |
Revenues | $ 28,563,000 | $ 57,763,000 | $ 82,715,000 | $ 92,392,000
Net loss | $ (47,688,000) | $ (1,508,000) | $ (140,801,000) | $ (80,447,000)
Earnings per share, basic (in dollars per share) | $ (0.33) | $ (0.01) | $ (0.98) | $ (0.61)
Earnings per share, diluted (in dollars per share) | $ (0.33) | $ (0.01) | $ (0.98) | $ (0.61)
Impairment of goodwill or indefinite-lived intangible assets |  |  | $ 0 |
Impairment of long-lived assets |  |  | 0 |
Letter of credit established as a deposit | $ 1,500,000 |  | 1,500,000 |
Sanofi S.A. |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |
Revenues | (759,000) | $ 1,498,000 | 1,258,000 | $ 3,789,000
Sanofi S.A. | Change in collaboration agreement scope | Collaboration agreement |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |
Revenues | 2,500,000 |  | 2,500,000 |
Net loss | $ 2,500,000 |  | $ 2,500,000 |
Earnings per share, basic (in dollars per share) | $ 0.02 | $ 0.02 |  |
Earnings per share, diluted (in dollars per share) |  |  | $ 0.02 | $ 0.02
Pfizer SB-525 |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |
Revenues | $ 0 |  | $ 0 |
Pfizer SB-525 | Change in collaboration agreement scope | Collaboration agreement |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |
Revenues |  | $ 5,800,000 |  | $ 8,900,000
Net loss |  | $ 5,800,000 |  | $ 8,900,000
Earnings per share, basic (in dollars per share) |  | $ 0.04 |  | $ 0.06

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