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v3.22.2.2

MAJOR CUSTOMERS, PARTNERSHIPS AND STRATEGIC ALLIANCES - Sanofi S.A. (Detail) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 102 Months Ended |
--- | --- | --- | --- | --- | --- | ---
Sep. 06, 2022 USD ($) | Jan. 31, 2014 USD ($) program | Sep. 30, 2022 USD ($) $ / shares | Sep. 30, 2021 USD ($) $ / shares | Sep. 30, 2022 USD ($) product milestone $ / shares | Sep. 30, 2021 USD ($) $ / shares | Jun. 28, 2022 USD ($) | Dec. 31, 2021 USD ($)
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Revenues |  |  | $ 26,460 | $ 28,563 | $ 84,069 | $ 82,715 |  |
Accounts receivable |  |  | 4,522 |  | 4,522 |  |  | $ 6,013
Decrease in research and development expense |  |  | 900 |  | 900 |  |  |
Increased net loss |  |  | $ 53,155 | $ 47,688 | $ 140,305 | $ 140,801 |  |
Increased earnings per share, diluted (in dollars per share) | $ / shares |  |  | $ (0.34) | $ (0.33) | $ (0.93) | $ (0.98) |  |
Increased earnings per share, basic (in dollars per share) | $ / shares |  |  | $ (0.34) | $ (0.33) | $ (0.93) | $ (0.98) |  |
Sanofi S.A. |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Number of research programs | program |  | 2 |  |  |  |  |  |
Revenues under agreement |  | $ 20,000 |  |  |  |  |  |
Revenues |  |  | $ 0 | $ (759) | $ 3,260 | $ 1,258 | $ 13,500 |
Number of products approved | product |  |  |  |  | 0 |  |  |
Post transition assistance period | 90 days |  |  |  |  |  |  |
Expenses reimbursable through December 31, 2023 (up to) | $ 7,000 |  |  |  |  |  |  |
Expenses reimbursable after December 31, 2023 (up to) | $ 5,300 |  |  |  |  |  |  |
Sanofi S.A. | Collaboration And License Agreement |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Revenues under agreement |  |  |  |  |  |  | 20,000 |
Number of milestones included in transaction price | milestone |  |  |  |  | 0 |  |  |
Collaborative arrangement transaction price |  |  |  |  |  |  | 96,300 |
Collaborative arrangement estimated reimbursable service costs |  |  |  |  |  |  | 62,800 |
Accounts receivable |  |  | 0 |  | $ 0 |  |  | 600
Deferred revenue |  |  | $ 0 |  | $ 0 |  |  | $ 1,100
Sanofi S.A. | Collaboration And License Agreement | Milestone three |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Milestone revenue receivable |  |  |  |  |  |  | $ 13,500 |
Sanofi S.A. | Collaboration agreement | Change In Collaboration Agreement Scope |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Revenues |  |  |  | (2,500) |  | (2,500) |  |
Increased net loss |  |  |  | $ 2,500 |  | $ 2,500 |  |
Increased earnings per share, diluted (in dollars per share) | $ / shares |  |  |  | $ 0.02 |  | $ 0.02 |  |
Increased earnings per share, basic (in dollars per share) | $ / shares |  |  |  | $ 0.02 |  | $ 0.02 |  |

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