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ORGANIZATION, BASIS OF PRESENTATION, AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 9 Months Ended 102 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Jun. 28, 2022
Change in Accounting Estimate [Line Items]          
Decreased revenue $ (26,460) $ (28,563) $ (84,069) $ (82,715)  
Increased net loss $ 53,155 $ 47,688 $ 140,305 $ 140,801  
Increased earnings per share, basic (in dollars per share) $ (0.34) $ (0.33) $ (0.93) $ (0.98)  
Increased earnings per share, diluted (in dollars per share) $ (0.34) $ (0.33) $ (0.93) $ (0.98)  
Letter of credit established as a deposit $ 1,500   $ 1,500    
Sanofi S.A.          
Change in Accounting Estimate [Line Items]          
Decreased revenue $ 0 $ 759 $ (3,260) $ (1,258) $ (13,500)
Sanofi S.A. | Change In Collaboration Agreement Scope | Collaboration agreement          
Change in Accounting Estimate [Line Items]          
Decreased revenue   2,500   2,500  
Increased net loss   $ 2,500   $ 2,500  
Increased earnings per share, basic (in dollars per share)   $ 0.02   $ 0.02  
Increased earnings per share, diluted (in dollars per share)   $ 0.02   $ 0.02