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MAJOR CUSTOMERS, PARTNERSHIPS AND STRATEGIC ALLIANCES - Pfizer Inc. (Details) $ in Millions | 1 Months Ended | 12 Months Ended | 70 Months Ended | 77 Months Ended
--- | --- | --- | --- | ---
Sep. 30, 2020 USD ($) | Dec. 31, 2017 USD ($) | May 31, 2017 USD ($) milestone | Dec. 31, 2020 USD ($) | Sep. 30, 2023 USD ($) milestone product | Sep. 30, 2023 USD ($) milestone
Pfizer Inc. |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Agreement termination, term |  |  | 15 years |  |  |
Pfizer Inc. | S B Five Two Five And Other Products |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Revenues under agreement |  |  | $ 70.0 |  |  |
Potential amount to be funded for achievement of specified commercialized and sales milestones |  |  | 266.5 |  |  |
Pfizer Inc. | S B Five Two Five And Other Products | Achievement of specified clinical development intellectual property and regulatory milestones |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Development and sales-based milestone payments to be received |  |  | 208.5 |  |  |
Pfizer Inc. | S B Five Two Five |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Milestone revenue receivable |  |  | 220.0 |  |  |
Pfizer Inc. | Other products |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Milestone revenue receivable |  |  | $ 175.0 |  |  |
Pfizer Inc. | License | Minimum |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Percentage of net sales per developed licensed product which will trigger royalties by counterparty |  | 14.00% | 14.00% |  |  |
Pfizer Inc. | License | Maximum |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Percentage of net sales per developed licensed product which will trigger royalties by counterparty |  | 20.00% | 20.00% |  |  |
Pfizer Inc. | C9ORF72 |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Revenues under agreement |  | $ 5.0 |  | $ 5.0 |  |
Development and sales-based milestone payments to be received | $ 5.0 |  |  |  |  |
Collaborative arrangement transaction price |  | $ 17.0 |  |  |  |
Pfizer SB-525 |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Revenues under agreement |  |  | $ 55.0 |  |  |
Collaborative arrangement transaction price |  |  | 134.0 |  |  |
Research service fees |  |  | $ 79.0 |  |  |
Pfizer SB-525 | S B Five Two Five And Other Products |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Collaborative arrangement, number of milestones achieved | milestone |  |  | 2 |  |  | 2
Milestone payments received |  |  |  |  |  | $ 55.0
Pfizer C9ORF72 |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Agreement termination, term |  | 15 years |  |  |  |
Pfizer C9ORF72 | C9ORF72 |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Revenues under agreement |  | $ 12.0 |  |  |  |
Milestone payments received |  | 12.0 |  |  | $ 5.0 |
Number of products approved | product |  |  |  |  | 0 |
Number of milestones included in transaction price | milestone |  |  |  |  | 0 |
Pfizer C9ORF72 | C9ORF72 | Achievement Of Specified Preclinical Development Clinical Development And First Commercial Sale Milestones | Maximum |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Development and sales-based milestone payments to be received |  | 60.0 |  |  |  |
Pfizer C9ORF72 | C9ORF72 | Achievement Of Commercial Milestones | Maximum |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |
Development and sales-based milestone payments to be received |  | $ 90.0 |  |  |  |

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