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INCOME TAXES (Tables)

12 Months Ended

Dec. 31, 2023

Income Tax Disclosure [Abstract]

Schedule of Domestic and Foreign Components of Loss Before Income Taxes

The domestic and foreign components of loss before income taxes were as follows (in thousands):

			Year Ended December 31,
			2023						2022						2021
Domestic			$	(173,375)					$	(216,573)					$	(185,216)
Foreign			(89,528)						24,724						7,225
Loss before income taxes			$	(262,903)					$	(191,849)					$	(177,991)

Schedule of Income Tax Expense (Benefit)

Income tax benefit for the year 2023 and the income tax expense for the years 2022 and 2021 consisted of the following (in thousands):

			Year Ended December 31,
			2023						2022						2021
Income tax expense:
Current:
Federal			$	—					$	—					$	—
State			—						—						—
Foreign			186						500						886
Subtotal			186						500						886
Deferred:
Federal			—						—						—
State			—						—						—
Foreign			(5,258)						(71)						(580)
Subtotal			(5,258)						(71)						(580)
Income tax expense			$	(5,072)					$	429					$	306

Schedule of Difference Between Income Tax Expense (Benefit) and Federal Statutory Income Tax Rate to Loss Before Income Taxes

The difference between the income tax benefit for the year 2023 and the income tax expense for the years 2022 and 2021 and the amount computed by applying the federal statutory income tax rate to loss before income taxes is explained as follows (in thousands):

			Year Ended December 31,
			2023						2022						2021
Tax at federal statutory rate			$	(55,210)					$	(40,288)					$	(37,372)
State taxes, net			(1,372)						(6,895)						(6,734)
Foreign rate differential			(4,273)						309						362
Global Intangible Low-taxed Income			791						1,002						637
Non-deductible stock-based compensation			4,770						3,545						2,770
Research credits			(7,020)						(6,694)						(5,230)
Change in valuation allowance			49,016						44,005						45,373
Transfer pricing settlement			—						4,343						—
Goodwill impairment			9,764						—						—
Other			(1,538)						1,102						500
Income tax expense			$	(5,072)					$	429					$	306

Schedule of Deferred Tax Assets and Liabilities and Based on Tax Jurisdictions

Significant components of the Company’s deferred tax assets and liabilities are as follows (in thousands):

			December 31,
			2023						2022
Assets:
Deferred tax assets:
Net operating loss carryforwards			$	196,719					$	174,129
Research and development tax credit carryforwards			54,336						44,264
Stock-based compensation			5,983						7,695
Deferred revenue			—						38,700
Capitalized research			71,675						37,985
Fixed assets			17,152						10,087
Intangible assets			101						—
Lease liability			8,559						10,074
Accruals and reserves			2,409						1,603
Other			259						283
Total deferred tax asset			357,193						324,820
Valuation allowance			351,430						301,840
Deferred tax assets			5,763						22,980
Liabilities:
Intangible assets			—						(13,512)
Operating lease right-of-use assets			(5,763)						(14,620)
Deferred tax liabilities			(5,763)						(28,132)
Total net deferred tax liabilities			$	—					$	(5,152)

The deferred tax assets and liabilities based on tax jurisdictions are presented on the Consolidated Balance Sheets as follows (in thousands):

			December 31,
			2023						2022
Deferred tax assets (included in Other non-current assets on the Consolidated Balance Sheets)			$	—					$	1,118
Deferred tax liabilities			—						(6,270)
Net deferred tax liabilities			$	—					$	(5,152)

Schedule of Unrecognized Tax Benefits

The following table summarizes the activity related to the Company’s unrecognized tax benefits (in thousands):

			December 31,
			2023						2022						2021
Beginning balance			$	18,179					$	15,062					$	12,892
Additions based on tax positions related to the current year			2,805						3,177						2,454
Additions for tax positions of prior years			29						278						130
Reductions for tax positions of prior years			(2,693)						(338)						(414)
Ending balance			$	18,320					$	18,179					$	15,062

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Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

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Tabular disclosure of income before income tax between domestic and foreign jurisdictions.

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Tabular disclosure of unrecognized tax benefits for which a material change is reasonably possible in the next twelve months, typically including the nature of the uncertainty, the event(s) that could cause a material change, and an estimate of the range of the reasonably possible change or a statement that an estimate of the range cannot be made. An unrecognized tax benefit is the difference between a tax position taken in a tax return and the amounts recognized in the financial statements for which it is more likely than not, based on the technical merits of the position, that the tax position will not be sustained upon examination.

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