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OTHER BALANCE SHEET DETAILS | 12 Months Ended
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Dec. 31, 2024
Balance Sheet Related Disclosures [Abstract] |
OTHER BALANCE SHEET DETAILS | OTHER BALANCE SHEET DETAILS Property and Equipment, Net Property and equipment, net consist of the following (in thousands):
| December 31,
| 2024 |  | 2023
Laboratory equipment | $ | 21,391 |  |  | $ | 34,630 |
Leasehold improvements | 24,923 |  |  | 29,809 |
Furniture and fixtures | 3,546 |  |  | 4,610 |
Manufacturing equipment | 7,845 |  |  | 7,784 |
Construction in progress | — |  |  | 1,087 |
| 57,705 |  |  | 77,920 |
Less: accumulated depreciation and amortization | (39,818) |  |  | (51,046) |
Property and equipment, net | $ | 17,887 |  |  | $ | 26,874 |
Depreciation and amortization expense was $5.1 million and $15.1 million during the years ended December 31, 2024 and 2023, respectively. During the year ended December 31, 2024, the Company recorded impairment losses of $1.9 million for its laboratory equipment and $0.7 million for its leasehold improvements. During the year ended December 31, 2023, the Company recorded impairment losses of $23.1 million for its leasehold improvements, $8.0 million for its laboratory equipment, $2.3 million for its manufacturing equipment, $1.6 million for its furniture and fixtures, and $1.6 million for its construction in progress. Intangible Assets The changes in intangible assets were as follows (in thousands):
| December 31,
| 2024 |  | 2023
Balance at beginning of year | $ | — |  |  | $ | 50,729 |
Foreign currency translation adjustment | — |  |  | 618 |
Impairment of indefinite-lived intangible asset | — |  |  | (51,347) |
Balance at end of year | $ | — |  |  | $ | — |
Goodwill The changes in goodwill were as follows (in thousands):
| December 31,
| 2024 |  | 2023
Balance at beginning of year | $ | — |  |  | $ | 37,552 |
Foreign currency translation adjustment | — |  |  | 586 |
Impairment of goodwill | — |  |  | (38,138) |
Balance at end of year | $ | — |  |  | $ | — |
Other Accrued Liabilities Other accrued liabilities consist of the following (in thousands):
| December 31,
| 2024 |  | 2023
Operating lease liabilities – current | $ | 4,313 |  |  | $ | 4,589 |
Accrued professional fees | 1,368 |  |  | 1,505 |
Accrued restructuring charges | 896 |  |  | 11,733 |
Accrued research and development expenses | 213 |  |  | 3,763 |
Other | 1,405 |  |  | 1,964 |
Total other accrued liabilities | $ | 8,195 |  |  | $ | 23,554 |

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- Definition The entire disclosure for supplemental balance sheet disclosures, including descriptions and amounts for assets, liabilities, and equity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 210 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/210/tableOfContent + Details
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