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INCOME TAXES (Tables)
 12 Months Ended
Dec. 31, 2024
Income Tax Disclosure [Abstract]  
Schedule of Domestic and Foreign Components of Loss Before Income Taxes
The domestic and foreign components of loss before income taxes were as follows (in thousands):
Year Ended December 31,
20242023
Domestic$(103,729)$(173,375)
Foreign5,621 (89,528)
Loss before income taxes$(98,108)$(262,903)
Schedule of Income Tax Expense (Benefit)
Income tax benefit for the years ended December 31, 2024 and 2023 consisted of the following (in thousands):
Year Ended December 31,
20242023
Income tax expense:
Current:
Federal$— $— 
State— — 
Foreign(167)186 
Subtotal(167)186 
Deferred:
Federal— — 
State— — 
Foreign— (5,258)
Subtotal— (5,258)
Income tax expense$(167)$(5,072)
Schedule of Difference Between Income Tax Expense (Benefit) and Federal Statutory Income Tax Rate to Loss Before Income Taxes
The difference between the income tax benefit for the years ended December 31, 2024 and 2023 and the amount computed by applying the federal statutory income tax rate to loss before income taxes is explained as follows (in thousands):
Year Ended December 31,
20242023
Tax at federal statutory rate$(20,603)$(55,210)
State taxes, net3,483 (1,372)
Foreign rate differential263 (4,273)
Global Intangible Low-taxed Income617 791 
Non-deductible stock-based compensation2,656 4,770 
Research credits(3,201)(7,020)
Change in valuation allowance16,172 49,016 
Goodwill impairment— 9,764 
Other446 (1,538)
Income tax expense$(167)$(5,072)
Schedule of Deferred Tax Assets and Liabilities and Based on Tax Jurisdictions Significant components of the Company’s deferred tax assets and liabilities are as follows (in thousands):
December 31,
20242023
Assets:
Deferred tax assets:
Net operating loss carryforwards$211,585 $196,719 
Research and development tax credit carryforwards58,409 54,336 
Stock-based compensation3,998 5,983 
Deferred revenue— — 
Capitalized research74,354 71,675 
Fixed assets15,648 17,152 
Intangible assets31 101 
Lease liability6,666 8,559 
Accruals and reserves331 2,409 
Other235 259 
Total deferred tax asset371,257 357,193 
Valuation allowance367,578 351,430 
Deferred tax assets3,679 5,763 
Liabilities:
Intangible assets— — 
Operating lease right-of-use assets(3,679)(5,763)
Deferred tax liabilities(3,679)(5,763)
Total net deferred tax liabilities$— $— 
Schedule of Unrecognized Tax Benefits Roll Forward
The following table summarizes the activity related to the Company’s unrecognized tax benefits (in thousands):
December 31,
20242023
Beginning balance$18,320 $18,179 
Additions based on tax positions related to the current year4,274 2,805 
Additions for tax positions of prior years26 29 
Reductions for tax positions of prior years(224)(2,693)
Statute lapse(259)— 
Ending balance$22,137 $18,320