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MAJOR CUSTOMERS, PARTNERSHIPS AND STRATEGIC ALLIANCES - Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease (Details) | 1 Months Ended | 3 Months Ended | 37 Months Ended | 88 Months Ended
--- | --- | --- | --- | ---
Dec. 31, 2017 USD ($) | Mar. 31, 2025 USD ($) | Mar. 31, 2024 USD ($) | Dec. 31, 2020 USD ($) | Mar. 31, 2025 USD ($) product milestone
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Revenues |  | $ 6,437,000 | $ 481,000 |  |
Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Agreement termination, term | 15 years |  |  |  |
Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease | License |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Milestone payments received | $ 12,000,000 |  |  |  | $ 5,000,000
Number of products approved | product |  |  |  |  | 0
Number of milestones included in transaction price | milestone |  |  |  |  | 0
Collaborative arrangement transaction price |  |  |  | $ 17,000,000 |
Revenues |  | $ 0 | $ 0 |  |
Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease | License | Maximum |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Percentage of net sales per developed licensed product which will trigger royalties by counterparty | 20.00% |  |  |  |
Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease | License | Maximum | Achievement Of Specified Preclinical Development Clinical Development And First Commercial Sale Milestones |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Development and sales-based milestone payments to be received | $ 60,000,000 |  |  |  |
Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease | License | Maximum | Achievement Of Commercial Milestones |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Development and sales-based milestone payments to be received | $ 90,000,000 |  |  |  |
Alexion Pharmaceuticals, Inc., AstraZeneca Rare Disease | License | Minimum |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |
Percentage of net sales per developed licensed product which will trigger royalties by counterparty | 14.00% |  |  |  |

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