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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
At-The-Market Offering
Stock Issuances Excluding At-The-Market Offering
Common Stock
Common Stock
At-The-Market Offering
Common Stock
Stock Issuances Excluding At-The-Market Offering
Additional Paid-in Capital
Additional Paid-in Capital
At-The-Market Offering
Additional Paid-in Capital
Stock Issuances Excluding At-The-Market Offering
Accumulated Deficit
Accumulated Other Comprehensive Loss
Beginning balance (in shares) at Dec. 31, 2023       178,133,548              
Beginning balance at Dec. 31, 2023 $ 82,887     $ 1,781     $ 1,492,077     $ (1,406,376) $ (4,595)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of common stock (in shares)           24,761,905          
Issuance of common stock     $ 21,788     $ 248     $ 21,540    
Issuance of common stock upon exercise of pre-funded warrants (in shares)       3,809,523              
Issuance of common stock upon exercise of pre-funded warrants 71     $ 38     33        
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (in shares)       1,116,678              
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (481)     $ 11     (492)        
Issuance of common stock under employee stock purchase plan (in shares)       379,486              
Issuance of common stock under employee stock purchase plan 146     $ 4     142        
Stock-based compensation 5,784           5,784        
Foreign currency translation adjustment (1,293)                   (1,293)
Net pension gains 238                   238
Unrealized loss on marketable securities, net of tax (233)                   (233)
Net loss (85,217)                 (85,217)  
Ending balance (in shares) at Jun. 30, 2024       208,201,140              
Ending balance at Jun. 30, 2024 23,690     $ 2,082     1,519,084     (1,491,593) (5,883)
Beginning balance (in shares) at Mar. 31, 2024       203,686,086              
Beginning balance at Mar. 31, 2024 56,697     $ 2,037     1,515,926     (1,455,465) (5,801)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of common stock upon exercise of pre-funded warrants (in shares)       3,809,523              
Issuance of common stock upon exercise of pre-funded warrants 71     $ 38     33        
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (in shares)       326,045              
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (79)     $ 3     (82)        
Issuance of common stock under employee stock purchase plan (in shares)       379,486              
Issuance of common stock under employee stock purchase plan 146     $ 4     142        
Stock-based compensation 3,065           3,065        
Foreign currency translation adjustment (313)                   (313)
Net pension gains 231                   231
Unrealized loss on marketable securities, net of tax 0                    
Net loss (36,128)                 (36,128)  
Ending balance (in shares) at Jun. 30, 2024       208,201,140              
Ending balance at Jun. 30, 2024 23,690     $ 2,082     1,519,084     (1,491,593) (5,883)
Beginning balance (in shares) at Dec. 31, 2024       212,837,679              
Beginning balance at Dec. 31, 2024 22,770     $ 2,128     1,532,489     (1,504,317) (7,530)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of common stock (in shares)         20,807,709 12,235,000          
Issuance of common stock   $ 17,627 21,139   $ 209 $ 122   $ 17,418 21,017    
Issuance of common stock upon exercise of pre-funded warrants (in shares)       22,398,393              
Issuance of common stock upon exercise of pre-funded warrants 224     $ 224              
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (in shares)       4,061,971              
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (2,647)     $ 41     (2,688)        
Issuance of common stock under employee stock purchase plan (in shares)       463,135              
Issuance of common stock under employee stock purchase plan 179     $ 4     175        
Stock-based compensation 4,822           4,822        
Foreign currency translation adjustment 5,980                   5,980
Net pension gains 91                   91
Unrealized loss on marketable securities, net of tax 0                    
Net loss (50,583)                 (50,583)  
Ending balance (in shares) at Jun. 30, 2025       272,803,887              
Ending balance at Jun. 30, 2025 19,602     $ 2,728     1,573,233     (1,554,900) (1,459)
Beginning balance (in shares) at Mar. 31, 2025       225,364,090              
Beginning balance at Mar. 31, 2025 4,906     $ 2,254     1,543,093     (1,534,914) (5,527)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                      
Issuance of common stock (in shares)         11,278,957 12,235,000          
Issuance of common stock   $ 7,266 $ 21,139   $ 113 $ 122   $ 7,153 $ 21,017    
Issuance of common stock upon exercise of pre-funded warrants (in shares)       22,398,393              
Issuance of common stock upon exercise of pre-funded warrants 224     $ 224              
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (in shares)       1,064,312              
Issuance of common stock upon exercise of stock options and vesting of restricted stock units, net of tax (420)     $ 11     (431)        
Issuance of common stock under employee stock purchase plan (in shares)       463,135              
Issuance of common stock under employee stock purchase plan 179     $ 4     175        
Stock-based compensation 2,226           2,226        
Foreign currency translation adjustment 4,068                   4,068
Net pension gains 0                    
Unrealized loss on marketable securities, net of tax 0                    
Net loss (19,986)                 (19,986)  
Ending balance (in shares) at Jun. 30, 2025       272,803,887              
Ending balance at Jun. 30, 2025 $ 19,602     $ 2,728     $ 1,573,233     $ (1,554,900) $ (1,459)