<SEC-DOCUMENT>0000814133-25-000099.txt : 20251112
<SEC-HEADER>0000814133-25-000099.hdr.sgml : 20251112
<ACCEPTANCE-DATETIME>20251112143458
ACCESSION NUMBER:		0000814133-25-000099
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251112
DATE AS OF CHANGE:		20251112

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SANGAMO THERAPEUTICS, INC
		CENTRAL INDEX KEY:			0001001233
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				680359556
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-59049
		FILM NUMBER:		251471821

	BUSINESS ADDRESS:	
		STREET 1:		501 CANAL BLVD.
		CITY:			RICHMOND
		STATE:			CA
		ZIP:			94084
		BUSINESS PHONE:		5109706000

	MAIL ADDRESS:	
		STREET 1:		501 CANAL BLVD.
		CITY:			RICHMOND
		STATE:			CA
		ZIP:			94084

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SANGAMO BIOSCIENCES INC
		DATE OF NAME CHANGE:	20000208

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			WASATCH ADVISORS LP
		CENTRAL INDEX KEY:			0000814133
		ORGANIZATION NAME:           	
		EIN:				870319391
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		505 WAKARA WAY
		STREET 2:		3RD FLOOR
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108
		BUSINESS PHONE:		8015330777

	MAIL ADDRESS:	
		STREET 1:		505 WAKARA WAY
		STREET 2:		3RD FLOOR
		CITY:			SALT LAKE CITY
		STATE:			UT
		ZIP:			84108

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	WASATCH ADVISORS INC
		DATE OF NAME CHANGE:	19990611
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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<submissionType>SCHEDULE 13G/A</submissionType> 	     <filerInfo>
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<cik>0000814133</cik>           <ccc>XXXXXXXX</ccc>
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</filer>       <liveTestFlag>LIVE</liveTestFlag>              </filerInfo>
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<amendmentNo>9</amendmentNo> 	  <securitiesClassTitle>Common Stock</securitiesClassTitle>       <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>       <issuerInfo>
<issuerCik>0001001233</issuerCik>         <issuerName>Sangamo Therapeutics Inc</issuerName>         <issuerCusip>800677106</issuerCusip>         <issuerPrincipalExecutiveOfficeAddress>
<com:street1>501 Canal Blvd</com:street1>           <com:city>Richmond</com:city>           <com:stateOrCountry>CA</com:stateOrCountry>           <com:zipCode>94804</com:zipCode>
</issuerPrincipalExecutiveOfficeAddress>
</issuerInfo>       <designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
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</coverPageHeader>   	<coverPageHeaderReportingPersonDetails> 	         <reportingPersonName>Wasatch Advisors LP</reportingPersonName> 	  <memberGroup>a</memberGroup>       <citizenshipOrOrganization>DE</citizenshipOrOrganization>       <reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>5587777.00</soleVotingPower>         <sharedVotingPower>0.00</sharedVotingPower>         <soleDispositivePower>6188358.00</soleDispositivePower>         <sharedDispositivePower>0.00</sharedDispositivePower>
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<issuerName>Sangamo Therapeutics Inc</issuerName>         <issuerPrincipalExecutiveOfficeAddress>501 Canal Blvd, Richmond, US-CA, 94804, US</issuerPrincipalExecutiveOfficeAddress>
</item1>        <item2>
<filingPersonName>Wasatch Advisors LP   </filingPersonName>         <principalBusinessOfficeOrResidenceAddress>505 Wakara Way, 3rd Floor, Salt Lake City, 84108, United States</principalBusinessOfficeOrResidenceAddress>         <citizenship>DELAWARE   </citizenship>
</item2>       <item3>
<notApplicableFlag>N</notApplicableFlag>          	                                                 <typeOfPersonFiling>IA</typeOfPersonFiling>
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<solePowerOrDirectToVote>5,587,777   </solePowerOrDirectToVote>           <sharedPowerOrDirectToVote>0   </sharedPowerOrDirectToVote>           <solePowerOrDirectToDispose>6,188,358   </solePowerOrDirectToDispose>           <sharedPowerOrDirectToDispose>0   </sharedPowerOrDirectToDispose>
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</item4>       <item5>
<notApplicableFlag>N</notApplicableFlag>         <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
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<notApplicableFlag>Y</notApplicableFlag>
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<notApplicableFlag>Y</notApplicableFlag>
</item8>       <item9>
<notApplicableFlag>Y</notApplicableFlag>
</item9>       <item10>
<notApplicableFlag>N</notApplicableFlag> 		<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. </certifications>
</item10>
</items> 	     <signatureInformation>
<reportingPersonName>Wasatch Advisors LP</reportingPersonName>       <signatureDetails>
<signature>Mike Yeates</signature>         <title>CEO</title>         <date>11/12/2025</date>
</signatureDetails>
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</SEC-DOCUMENT>
