<SEC-DOCUMENT>0001213900-19-018314-index.html : 20190917
<SEC-HEADER>0001213900-19-018314.hdr.sgml : 20190917
<ACCEPTANCE-DATETIME>20190917171909
ACCESSION NUMBER:		0001213900-19-018314
CONFORMED SUBMISSION TYPE:	F-1/A
PUBLIC DOCUMENT COUNT:		13
FILED AS OF DATE:		20190917
DATE AS OF CHANGE:		20190917

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Tiziana Life Sciences plc
		CENTRAL INDEX KEY:			0001723069
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		F-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-233020
		FILM NUMBER:		191097746

	BUSINESS ADDRESS:	
		STREET 1:		3RD FLOOR, 11-12 ST. JAMES'S SQUARE
		CITY:			LONDON, ENGLAND
		STATE:			X0
		ZIP:			SW1Y 4LB
		BUSINESS PHONE:		0044(0) 207-495-2379

	MAIL ADDRESS:	
		STREET 1:		3RD FLOOR, 11-12 ST. JAMES'S SQUARE
		CITY:			LONDON, ENGLAND
		STATE:			X0
		ZIP:			SW1Y 4LB
</SEC-HEADER>
<DOCUMENT>
<TYPE>F-1/A
<SEQUENCE>1
<FILENAME>ff12019a1_tizianalife.htm
<DESCRIPTION>AMENDMENT NO. 1 TO FORM F-1
<TEXT>
Document 1 - file: ff12019a1_tizianalife.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>ff12019a1ex5-1_tiziana.htm
<DESCRIPTION>OPINION OF COOLEY (UK) LLP
<TEXT>
Document 2 - file: ff12019a1ex5-1_tiziana.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>ff12019a1ex23-1_tiziana.htm
<DESCRIPTION>CONSENT OF MAZARS LLP, INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
<TEXT>
Document 3 - file: ff12019a1ex23-1_tiziana.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>ex5-1_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: ex5-1_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>tiziana_logo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: tiziana_logo.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>image_01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: image_01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>image_02.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: image_02.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>image_011.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: image_011.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>image_03.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: image_03.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>image_04.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: image_04.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>image_05.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: image_05.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>linechart.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: linechart.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>image_06.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: image_06.jpg

</DOCUMENT>
</SEC-DOCUMENT>