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Financial Instruments (Details) - Schedule of Financial Liabilities Based on Contractual Undiscounted Payments - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2023 | Dec. 31, 2022
Financial Instruments (Details) - Schedule of Financial Liabilities Based on Contractual Undiscounted Payments [Line Items] |  |
Trade payables | $ 4,137 | $ 4,962
Lease liabilities | 138 | 130
Related party payables |  |
Total | 4,275 | 5,092
Less than 3 months [Member] |  |
Financial Instruments (Details) - Schedule of Financial Liabilities Based on Contractual Undiscounted Payments [Line Items] |  |
Trade payables | 2,223 | 1,230
Lease liabilities | 34 | 32
Related party payables |  |
Total | 2,354 | 1,262
3 to 12 months [Member] |  |
Financial Instruments (Details) - Schedule of Financial Liabilities Based on Contractual Undiscounted Payments [Line Items] |  |
Trade payables | 1,914 | 3,732
Lease liabilities | 104 | 98
Related party payables |  |
Total | $ 1,921 | $ 3,830

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- Definition The amount of liabilities related to the entity's leases. Lease is a contract, or part of a contract, that conveys the right to use an underlying asset for a period of time in exchange for consideration. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IFRS -Number 16 -IssueDate 2023-01-01 -Paragraph 47 -Subparagraph b -URI https://taxonomy.ifrs.org/xifrs-link?type=IFRS&num=16&code=ifrs-tx-2023-en-r&anchor=para_47_b&doctype=Standard -URIDate 2023-03-23 + Details
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Balance Type: | credit
Period Type: | instant

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- Definition The amount of trade payables and other payables. [Refer: Trade payables; Other payables] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IAS -Number 1 -IssueDate 2023-01-01 -Paragraph 54 -Subparagraph k -URI https://taxonomy.ifrs.org/xifrs-link?type=IAS&num=1&code=ifrs-tx-2023-en-r&anchor=para_54_k&doctype=Standard -URIDate 2023-03-23 + Details
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Balance Type: | credit
Period Type: | instant

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- References No definition available. + Details
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- References No definition available. + Details
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Namespace Prefix: | tlsa_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

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- References No definition available. + Details
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Namespace Prefix: | tlsa_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Details
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- Details
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