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Share Based Payments (Details) - Schedule of Estimated the Fair Value of Warrants Using - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Schedule of Estimated the Fair Value of Warrants Using [Abstract] |  |  |
Outstanding beginning | $ 697 | $ 697 | $ 697
Exercised | (438) |  |
Expired | (259) |  |
Outstanding ending |  | $ 697 | $ 697

X
- Definition Representation amount of outstanding. + References No definition available. + Details
Name: | tlsa_FairValueOutstanding
Namespace Prefix: | tlsa_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Representation amount of exercised. + References No definition available. + Details
Name: | tlsa_OutstandingExercised
Namespace Prefix: | tlsa_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Representtion amount of expired. + References No definition available. + Details
Name: | tlsa_OutstandingExpired
Namespace Prefix: | tlsa_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- References No definition available. + Details
Name: | tlsa_ScheduleOfEstimatedTheFairValueOfWarrantsUsingAbstract
Namespace Prefix: | tlsa_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration