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Collaboration and License Agreements - Additional Information (Details) - USD ($) $ in Thousands | 3 Months Ended |
--- | --- | ---
Mar. 31, 2025 | Mar. 31, 2024 | Feb. 28, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenue | $ 20,558 | $ 59,120 |
Vertex |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Strategic collaboration agreement, term |  |  | 4 years
Revenue | 20,600 | 58,100 |
Cumulative catch-up adjustment | 12,300 | 17,400 |
Vertex | Recognition of upfront and milestone payments |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenue | 18,900 | 38,700 |
Vertex | Collaboration service revenue |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenue | 1,600 | $ 2,000 |
Vertex | License |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Revenue, remaining performance obligation, amount | $ 1,700 |  |

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