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Statements of Cash Flows (USD $)
 3 Months Ended 130 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Mar. 31, 2014
Operating activities      
Net (loss) income $ (5,101,850) $ 459,687 $ (68,377,259)
Adjustments to reconcile net (loss) income net cash used in operating activities:      
Depreciation 34,620 31,940 1,173,585
Loss on retirement of property and equipment     172,584
Amortization of imputed interest on notes payable     19,200
Amortization of debt discount     205,899
Sales proceeds     3,531
Compensation expense from stock option grants 292,216 108,011 1,708,116
Issuance of Series A Convertible Preferred Stock for services     300,000
Acquired in process research and development paid with Series A Convertible Preferred Stock and notes payable     660,802
Changes in assets and liabilities      
Prepaid expenses and other current assets 1,854,053 54,889 (636,319)
Accounts payable 652,147 (319,431) 1,797,062
Accrued expenses (292,758) (381,638) 1,521,697
Deferred revenue   (3,807,592)  
Deferred rent (25,476) (22,374) 175,471
Net cash used in operating activities (2,587,048) (3,876,508) (61,275,631)
Investing activities      
Restricted cash     (254,900)
Purchases of property and equipment (13,920) (6,824) (1,556,387)
Net cash used in investing activities (13,920) (6,824) (1,811,287)
Financing activities      
Proceeds from issuance of Convertible Preferred Stock, net of issuance costs     45,120,901
Proceeds from issuance of common stock, net of issuance costs 57,256,393   57,256,393
Proceeds from notes payable     18,488,929
Proceeds from exercise of stock options     560,129
Repayments of notes payable     (1,373,406)
Net cash provided by financing activities 57,256,393   120,052,946
Net increase (decrease) in cash and cash equivalents 54,655,425 (3,883,332) 56,966,028
Cash and cash equivalents, beginning of period 2,310,603 17,372,832  
Cash and cash equivalents, end of period 56,966,028 13,489,500 56,966,028
Series A Convertible Preferred Stock [Member]
      
Supplemental schedule of noncash financing activities:      
Conversion of Series A Convertible Preferred Stock to Common Stock $ 38,805,055   $ 38,805,055