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Stockholders' Equity - Stock-Based Compensation Expense (Detail) (USD $)
3 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Total share based compensation expense $ 292,216 $ 108,011
Research and Development [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Total share based compensation expense 91,467 59,261
General and Administrative Expense [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Total share based compensation expense $ 200,749 $ 48,750