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Balance Sheets (USD $)	Mar. 31, 2015	Dec. 31, 2014
Current assets:
Cash and cash equivalents	$ 46,566,894us-gaap_CashAndCashEquivalentsAtCarryingValue	$ 55,198,923us-gaap_CashAndCashEquivalentsAtCarryingValue
Prepaid expenses and other current assets	777,079us-gaap_PrepaidExpenseAndOtherAssetsCurrent	916,249us-gaap_PrepaidExpenseAndOtherAssetsCurrent
Total current assets	47,343,973us-gaap_AssetsCurrent	56,115,172us-gaap_AssetsCurrent
Property and equipment, net	420,365us-gaap_PropertyPlantAndEquipmentNet	452,270us-gaap_PropertyPlantAndEquipmentNet
Prepaid research and development expenses	696,531us-gaap_PrepaidExpenseNoncurrent	696,531us-gaap_PrepaidExpenseNoncurrent
Total assets	48,460,869us-gaap_Assets	57,263,973us-gaap_Assets
Current liabilities:
Accounts payable	1,183,492us-gaap_AccountsPayableCurrent	874,028us-gaap_AccountsPayableCurrent
Accrued bonuses	226,015us-gaap_AccruedBonusesCurrent	753,786us-gaap_AccruedBonusesCurrent
Accrued expenses	2,626,207us-gaap_AccruedLiabilitiesCurrent	4,735,719us-gaap_AccruedLiabilitiesCurrent
Current portion of deferred rent	67,965us-gaap_DeferredRentCreditCurrent	97,012us-gaap_DeferredRentCreditCurrent
Total current liabilities	4,103,679us-gaap_LiabilitiesCurrent	6,460,545us-gaap_LiabilitiesCurrent
Total liabilities	4,103,679us-gaap_Liabilities	6,460,545us-gaap_Liabilities
Stockholders' equity:
Preferred Stock; $0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding at March 31, 2015 and December 31, 2014
Common stock; $0.001 par value; 100,000,000 shares authorized, 19,007,133 shares issued and outstanding at March 31, 2015; 18,939,838 shares issued and outstanding at December 31, 2014	19,008us-gaap_CommonStockValue	18,940us-gaap_CommonStockValue
Additional paid-in capital	125,844,286us-gaap_AdditionalPaidInCapital	125,181,463us-gaap_AdditionalPaidInCapital
Accumulated deficit	(81,506,104)us-gaap_RetainedEarningsAccumulatedDeficit	(74,396,975)us-gaap_RetainedEarningsAccumulatedDeficit
Total stockholders' equity	44,357,190us-gaap_StockholdersEquity	50,803,428us-gaap_StockholdersEquity
Total liabilities and stockholders' equity	$ 48,460,869us-gaap_LiabilitiesAndStockholdersEquity	$ 57,263,973us-gaap_LiabilitiesAndStockholdersEquity

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