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Significant Accounting Policies - Additional Information (Detail) - USD ($)
1 Months Ended 6 Months Ended 18 Months Ended
Jun. 30, 2015
May. 31, 2014
Jun. 30, 2015
Mar. 31, 2013
Dec. 31, 2014
Schedule Of Accounting Policies [Line Items]          
Carrying value of cash held in money market funds $ 39,500,000   $ 39,500,000   $ 55,000,000
Expected term (years)     6 years 3 months    
Pfizer License Agreement [Member]          
Schedule Of Accounting Policies [Line Items]          
Allowance for collecting on all outstanding accounts 0   $ 0    
Amount of revenue recognition     20,000,000    
Revenue $ 20,000,000 $ 15,000,000 $ 20,000,000    
Pfizer License Agreement [Member] | Up-Front Payment Arrangement [Member]          
Schedule Of Accounting Policies [Line Items]          
Amount received and recognized as revenue       $ 22,500,000  
Joint steering committees period       1 year 6 months  
Maximum [Member]          
Schedule Of Accounting Policies [Line Items]          
Share-based compensation arrangement by share-based payment award, option grant term     10 years