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Research and License Agreements - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 18 Months Ended
Feb. 29, 2016
Jun. 30, 2015
May. 31, 2014
Oct. 31, 2011
Mar. 31, 2016
Mar. 31, 2015
Mar. 31, 2013
Dec. 31, 2015
Research and Development Arrangement, Contract to Perform for Others [Line Items]                
Milestone license fees recorded               $ 2,000,000
Accrued liability paid for research agreement $ 2,000,000              
Research and development expenses         $ 5,518,722 $ 5,207,730    
University Of Basel Agreement [Member]                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                
Percentage of obligations payable for all future milestone and royalty payments received with respect to rivipansel         10.00%      
Milestone license fees recorded               2,000,000
Pfizer License Agreement [Member]                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                
Non-refundable payment against milestone payment               $ 20,000,000
Potential milestone payments upon the achievement of specified development milestones       $ 115,000,000        
Potential milestone payments upon the achievement of specified regulatory milestones       70,000,000        
Potential milestone payments upon the achievement specified levels of annual net sales of licensed products       135,000,000        
Payment made on execution of milestone agreement       $ 22,500,000        
Period of up-front payment         1 year 6 months      
Revenue   $ 20,000,000 $ 15,000,000          
Pfizer License Agreement [Member] | Up-Front Payment Arrangement [Member]                
Research and Development Arrangement, Contract to Perform for Others [Line Items]                
Amount received and recognized as revenue             $ 22,500,000