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Income Taxes - Additional Information (Detail) - USD ($) | Dec. 31, 2016 | Dec. 31, 2015
--- | --- | ---
NOL to be recognized in APIC when realized | $ 250,359 |
Unrecognized tax benefits | 0 | $ 0
Research tax credit carryforward |  |
Tax credits available to carry forward | 7,394,601 |
Orphan drug credit carryforward |  |
Tax credits available to carry forward | 7,593,921 |
U.S. Federal And State |  |
Net operating losses | $ 87,591,753 |

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