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Summary of Significant Accounting Policies - Property and Equipment (Detail)
12 Months Ended
Dec. 31, 2017
Furniture and Fixtures  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P7Y
Laboratory Equipment  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P5Y
Office Equipment  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P5Y
Computer Equipment  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P5Y
Computer Software  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P3Y
Minimum  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P3Y
Maximum  
Property, Plant and Equipment [Line Items]  
Property and Equipment Estimated useful lives P7Y