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Unaudited Statements of Cash Flows - USD ($)
 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Operating activities    
Net loss $ (22,791,607) $ (16,073,109)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 138,317 123,916
Loss on disposal of property and equipment 168  
Stock-based compensation expense 2,266,219 1,833,955
Changes in assets and liabilities    
Prepaid expenses and other current assets (188,632) (23,652)
Prepaid research and development expenses (1,510,607)  
Accounts payable 592,413 (990,099)
Accrued expenses and bonuses (1,738,448) (31,672)
Deferred rent (34,649) (8,948)
Net cash used in operating activities (23,266,826) (15,169,609)
Investing activities    
Purchases of property and equipment (42,054) (227,173)
Net cash used in investing activities (42,054) (227,173)
Financing activities    
Proceeds from issuance of common stock, net of issuance costs 128,425,080 94,405,507
Proceeds from exercise of stock options and warrants 393,786 97,562
Net cash provided by financing activities 128,818,866 94,503,069
Net change in cash and cash equivalents 105,509,986 79,106,287
Cash and cash equivalents, beginning of period 123,924,738 40,041,641
Cash and cash equivalents, end of period $ 229,434,724 119,147,928
Non-cash investing activities and financing activities    
Issuance costs associated with financing included in accounts payable and accrued expenses   $ 133,185