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Property and Equipment (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Property, Plant and Equipment [Line Items]          
Property and equipment $ 2,483,864   $ 2,483,864   $ 2,416,371
Less accumulated depreciation (1,515,313)   (1,515,313)   (1,309,472)
Property and equipment, net 968,551   968,551   1,106,899
Depreciation of property and equipment 68,477 $ 70,060 206,794 $ 193,976  
Furniture and Fixtures          
Property, Plant and Equipment [Line Items]          
Property and equipment 332,073   332,073   314,024
Laboratory Equipment          
Property, Plant and Equipment [Line Items]          
Property and equipment 1,342,973   1,342,973   1,325,667
Office Equipment          
Property, Plant and Equipment [Line Items]          
Property and equipment 11,085   11,085   11,085
Computer Equipment          
Property, Plant and Equipment [Line Items]          
Property and equipment 224,568   224,568   192,430
Leasehold Improvements          
Property, Plant and Equipment [Line Items]          
Property and equipment $ 573,165   $ 573,165   $ 573,165