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Unaudited Statements of Cash Flows - USD ($)
 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Operating activities    
Net loss $ (34,366,718) $ (24,023,210)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 206,794 193,976
Loss on disposal of property and equipment 168  
Stock-based compensation expense 3,437,341 2,796,301
Changes in assets and liabilities    
Prepaid expenses and other current assets 689,698 (537,244)
Prepaid research and development expenses (1,510,607)  
Accounts payable (1,987,696) 66,512
Accrued expenses and bonuses 232,534 125,250
Deferred rent (52,644) (21,072)
Net cash used in operating activities (33,351,130) (21,399,487)
Investing activities    
Purchases of property and equipment (68,614) (259,860)
Net cash used in investing activities (68,614) (259,860)
Financing activities    
Proceeds from issuance of common stock, net of issuance costs 128,425,080 94,269,213
Proceeds from exercise of stock options and warrants 898,560 221,027
Net cash provided by financing activities 129,323,640 94,490,240
Net change in cash and cash equivalents 95,903,896 72,830,893
Cash and cash equivalents, beginning of period 123,924,738 40,041,641
Cash and cash equivalents, end of period $ 219,828,634 $ 112,872,534