Unaudited Statements of Operations and Comprehensive Loss - USD ($)	3 Months Ended
Mar. 31, 2019	Mar. 31, 2018
Statements of Operations and Comprehensive Loss
Revenue
Costs and expenses:
Research and development expense	11,772,666	9,021,423
General and administrative expense	3,360,448	2,855,125
Total costs and expenses	15,133,114	11,876,548
Loss from operations	(15,133,114)	(11,876,548)
Interest income	1,049,217	363,704
Net loss and comprehensive loss	$ (14,083,897)	$ (11,512,844)
Basic and diluted net loss per common share (in dollars per share)	$ (0.33)	$ (0.33)
Basic and diluted weighted average number of common shares (in shares)	43,166,967	35,156,090

The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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