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Stockholders' Equity - Stock-Based Compensation Expense (Details) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Stock-based compensation expense
Total stock-based compensation expense	$ 1,590,860	$ 1,690,351	$ 4,767,206	$ 5,274,173
Research and Development
Stock-based compensation expense
Total stock-based compensation expense	586,001	763,081	1,884,295	2,246,118
General and Administrative Expense
Stock-based compensation expense
Total stock-based compensation expense	$ 1,004,859	$ 927,270	$ 2,882,911	$ 3,028,055

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- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

+ References

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-Topic 718
-SubTopic 10
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