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Stockholders' Equity - Inducement Plan (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 09, 2014
installment
shares
Jan. 31, 2022
USD ($)
shares
Aug. 31, 2021
shares
Jan. 31, 2020
installment
shares
Mar. 31, 2022
USD ($)
shares
Mar. 31, 2021
USD ($)
shares
Dec. 31, 2021
USD ($)
shares
Share-based Compensation Arrangement by Share-based Payment Award              
Increase in number of shares of common stock   3,000,000          
Fair value of shares vested | $         $ 10,667 $ 2,205  
Inducement Plan              
Share-based Compensation Arrangement by Share-based Payment Award              
Period from date of termination that any vested options shall expire       90 days      
Expiration period       10 years      
Unrecognized compensation expense related to unvested options | $         $ 1,796,675    
Period for unrecognized compensation expense related to unvested options yet has not been recognized         3 years 4 months 24 days    
Increase in number of shares of common stock     2,000,000        
Aggregate intrinsic value | $         $ 16,000    
Stock options granted         335,000    
Options exercised         0 0  
Inducement Plan | Upon first anniversary of start date              
Share-based Compensation Arrangement by Share-based Payment Award              
Vesting percentage       25.00%      
Inducement Plan | Each month after the first anniversary              
Share-based Compensation Arrangement by Share-based Payment Award              
Number of monthly installments | installment       36      
2013 Equity Incentive Plan              
Share-based Compensation Arrangement by Share-based Payment Award              
Period from date of termination that any vested options shall expire 90 days            
Expiration period 10 years            
Common stock authorized         9,506,767    
Period for unrecognized compensation expense related to unvested options yet has not been recognized         2 years 3 months 18 days    
Increase in number of shares of common stock         2,619,622    
Aggregate intrinsic value | $         $ 55,000    
Stock options granted         1,825,100    
Fair value of shares vested | $         $ 1,263,094 $ 2,269,172  
Options exercised         0 0  
2013 Equity Incentive Plan | Stock options vesting based on performance              
Share-based Compensation Arrangement by Share-based Payment Award              
Maximum fair value of option excluded from the unrecognized compensation expense | $         $ 825,353   $ 825,353
2013 Equity Incentive Plan | Stock options vesting based on performance | Employees              
Share-based Compensation Arrangement by Share-based Payment Award              
Stock options granted   214,200          
Maximum fair value of option excluded from the unrecognized compensation expense | $   $ 171,360          
2013 Equity Incentive Plan | Stock options vesting based on performance | Newly hired employees              
Share-based Compensation Arrangement by Share-based Payment Award              
Stock options granted         584,200   584,200
2013 Equity Incentive Plan | Upon first anniversary of start date              
Share-based Compensation Arrangement by Share-based Payment Award              
Vesting percentage 25.00%            
2013 Equity Incentive Plan | Each month after the first anniversary              
Share-based Compensation Arrangement by Share-based Payment Award              
Number of monthly installments | installment 36            
2013 Equity Incentive Plan | Vesting upon FDA Approval | Stock options vesting based on performance | Employees              
Share-based Compensation Arrangement by Share-based Payment Award              
Vesting percentage   50.00%          
2013 Equity Incentive Plan | Vesting upon First Commercial Sale | Stock options vesting based on performance | Employees              
Share-based Compensation Arrangement by Share-based Payment Award              
Vesting percentage   50.00%          
Common Stock              
Share-based Compensation Arrangement by Share-based Payment Award              
Options exercised           3,785  
Common Stock | Inducement Plan              
Share-based Compensation Arrangement by Share-based Payment Award              
Common stock authorized       500,000      
Common Stock | 2013 Equity Incentive Plan              
Share-based Compensation Arrangement by Share-based Payment Award              
Common stock authorized 1,000,000