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Statements of Operations and Comprehensive Loss - USD ($) | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021
Statements of Operations and Comprehensive Loss |  |  |  |
Revenue from collaboration and license agreements | $ 75,000 | $ 142 | $ 75,000 | $ 1,055,582
Costs and expenses: |  |  |  |
Research and development expense | 7,973,278 | 10,167,282 | 17,577,200 | 21,314,517
General and administrative expense | 5,454,877 | 4,237,342 | 10,511,065 | 8,425,452
Total costs and expenses | 13,428,155 | 14,404,624 | 28,088,265 | 29,739,969
Loss from operations | (13,353,155) | (14,404,482) | (28,013,265) | (28,684,387)
Interest income | 85,588 | 5,221 | 92,657 | 11,067
Net loss and comprehensive loss | $ (13,267,567) | $ (14,399,261) | $ (27,920,608) | $ (28,673,320)
Basic net loss per common share (in dollars per share) | $ (0.25) | $ (0.28) | $ (0.53) | $ (0.56)
Diluted net loss per common share (in dollars per share) | $ (0.25) | $ (0.28) | $ (0.53) | $ (0.56)
Basic weighted-average number of common shares outstanding (in shares) | 52,407,347 | 51,539,010 | 52,369,369 | 51,118,096
Diluted weighted-average number of common shares outstanding (in shares) | 52,407,347 | 51,539,010 | 52,369,369 | 51,118,096

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