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v3.23.1

Statements of Operations and Comprehensive Loss - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Statements of Operations and Comprehensive Loss |  |  |
Revenue from collaboration and license agreements | $ 75,000 | $ 1,159,767 | $ 10,162,935
Costs and expenses: |  |  |
Research and development expense | 28,390,879 | 47,491,567 | 44,929,198
General and administrative expense | 19,087,443 | 17,115,405 | 16,743,127
Total costs and expenses | 47,478,322 | 64,606,972 | 61,672,325
Loss from operations | (47,403,322) | (63,447,205) | (51,509,390)
Interest income | 714,520 | 19,768 | 482,487
Net loss and comprehensive loss | $ (46,688,802) | $ (63,427,437) | $ (51,026,903)
Basic net loss per common share (in dollars per share) | $ (0.89) | $ (1.23) | $ (1.12)
Diluted net loss per common share (in dollars per share) | $ (0.89) | $ (1.23) | $ (1.12)
Basic weighted-average number of common shares outstanding (in shares) | 52,531,173 | 51,453,204 | 45,721,139
Diluted weighted-average number of common shares outstanding (in shares) | 52,531,173 | 51,453,204 | 45,721,139

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