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v3.23.1

Stockholders' Equity - Inducement Plan (Details) | 1 Months Ended | 12 Months Ended |
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May 31, 2022 shares | Jan. 31, 2022 USD ($) shares | Aug. 31, 2021 shares | Jan. 31, 2020 installment shares | Dec. 31, 2022 USD ($) shares | Dec. 31, 2021 USD ($) shares | Dec. 31, 2020 USD ($) shares | Jan. 09, 2014 shares
Inducement Plan |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Expiration period |  |  |  | 10 years |  |  |  |
Unrecognized compensation expense related to unvested options | $ |  |  |  |  | $ 1,473,466 |  |  |
Intrinsic value of options exercised | $ |  |  |  |  |  | $ 1,944,000 |  |
Cash proceeds from exercise of stock options | $ |  |  |  |  |  | $ 20,790 |  |
Period for unrecognized compensation expense related to unvested options yet has not been recognized |  |  |  |  | 2 years 8 months 12 days |  |  |
Common stock shares issued |  |  |  |  |  | 10,092 |  |
Aggregate intrinsic value | $ |  |  |  |  | $ 2,867,000 |  |  |
Stock options granted |  |  |  |  | 535,000 |  |  |
Fair value of shares vested | $ |  |  |  |  | $ 604,440 | $ 73,334 |  |
Options exercised |  |  |  |  | 0 |  | 0 |
Inducement Plan | Stock options vesting based on performance | Employees |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Stock options granted |  |  |  |  | 584,200 | 584,200 |  |
Maximum fair value of option excluded from the unrecognized compensation expense | $ |  |  |  |  | $ 825,353 | $ 825,353 |  |
Inducement Plan | Upon first anniversary of start date |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Vesting percentage |  |  |  | 25.00% |  |  |  |
Number of monthly installments | installment |  |  |  | 36 |  |  |  |
Period from date of termination that any vested options shall expire |  |  |  | 90 days |  |  |  |
2013 Equity Incentive Plan |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Period from date of termination that any vested options shall expire |  |  |  |  | 90 days |  |  |
Expiration period |  |  |  |  | 10 years |  |  |
Period for unrecognized compensation expense related to unvested options yet has not been recognized |  |  |  |  | 2 years |  |  |
Aggregate intrinsic value | $ |  |  |  |  | $ 3,506,000 |  |  |
Stock options granted |  |  |  |  | 2,020,800 |  |  |
Fair value of shares vested | $ |  |  |  |  | $ 3,306,412 | $ 5,936,641 | $ 7,347,548 |
Options exercised |  |  |  |  | 0 | 0 | 0 |
2013 Equity Incentive Plan | Stock options vesting based on performance | Employees |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Shares available for future grants |  | 189,600 |  |  |  |  |  |
Maximum fair value of option excluded from the unrecognized compensation expense | $ |  | $ 151,680 |  |  |  |  |  |
2013 Equity Incentive Plan | Upon first anniversary of start date |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Vesting percentage |  |  |  |  | 25.00% |  |  |
2013 Equity Incentive Plan | Each month after the first anniversary |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Vesting percentage |  |  |  |  | 2.083% |  |  |
2013 Equity Incentive Plan | Vesting upon FDA Approval | Stock options vesting based on performance | Employees |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Vesting percentage |  | 50.00% |  |  |  |  |  |
2013 Equity Incentive Plan | Vesting upon First Commercial Sale | Stock options vesting based on performance | Employees |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Vesting percentage |  | 50.00% |  |  |  |  |  |
Common Stock | Inducement Plan |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Common stock authorized |  |  |  | 500,000 |  |  |  |
Increase in number of shares of common stock |  | 3,000,000 | 2,000,000 |  |  |  |  |
Shares available for future grants |  |  |  |  | 656,383 |  |  |
Common Stock | 2013 Equity Incentive Plan |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award |  |  |  |  |  |  |  |
Common stock authorized |  |  |  |  | 9,506,767 |  |  | 1,000,000
Increase in number of shares of common stock | 2,619,622 |  |  |  |  |  |  |
Shares available for future grants |  |  |  |  | 1,976,154 |  |  |

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