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Stockholders' Equity - Inducement Plan (Details)	1 Months Ended				12 Months Ended
	May 31, 2022 shares	Jan. 31, 2022 USD ($) shares	Aug. 31, 2021 shares	Jan. 31, 2020 installment shares	Dec. 31, 2022 USD ($) shares	Dec. 31, 2021 USD ($) shares	Dec. 31, 2020 USD ($) shares	Jan. 09, 2014 shares
Inducement Plan
Share-based Compensation Arrangement by Share-based Payment Award
Expiration period				10 years
Unrecognized compensation expense related to unvested options | $					$ 1,473,466
Intrinsic value of options exercised | $						$ 1,944,000
Cash proceeds from exercise of stock options | $						$ 20,790
Period for unrecognized compensation expense related to unvested options yet has not been recognized					2 years 8 months 12 days
Common stock shares issued						10,092
Aggregate intrinsic value | $					$ 2,867,000
Stock options granted					535,000
Fair value of shares vested | $					$ 604,440	$ 73,334
Options exercised					0		0
Inducement Plan | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Stock options granted					584,200	584,200
Maximum fair value of option excluded from the unrecognized compensation expense | $					$ 825,353	$ 825,353
Inducement Plan | Upon first anniversary of start date
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage				25.00%
Number of monthly installments | installment				36
Period from date of termination that any vested options shall expire				90 days
2013 Equity Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award
Period from date of termination that any vested options shall expire					90 days
Expiration period					10 years
Period for unrecognized compensation expense related to unvested options yet has not been recognized					2 years
Aggregate intrinsic value | $					$ 3,506,000
Stock options granted					2,020,800
Fair value of shares vested | $					$ 3,306,412	$ 5,936,641	$ 7,347,548
Options exercised					0	0	0
2013 Equity Incentive Plan | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Shares available for future grants		189,600
Maximum fair value of option excluded from the unrecognized compensation expense | $		$ 151,680
2013 Equity Incentive Plan | Upon first anniversary of start date
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage					25.00%
2013 Equity Incentive Plan | Each month after the first anniversary
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage					2.083%
2013 Equity Incentive Plan | Vesting upon FDA Approval | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage		50.00%
2013 Equity Incentive Plan | Vesting upon First Commercial Sale | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage		50.00%
Common Stock | Inducement Plan
Share-based Compensation Arrangement by Share-based Payment Award
Common stock authorized				500,000
Increase in number of shares of common stock		3,000,000	2,000,000
Shares available for future grants					656,383
Common Stock | 2013 Equity Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award
Common stock authorized					9,506,767			1,000,000
Increase in number of shares of common stock	2,619,622
Shares available for future grants					1,976,154

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