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Stockholders' Equity - Inducement Plan (Details)		1 Months Ended		3 Months Ended		12 Months Ended
	Jan. 09, 2014 installment shares	Jan. 31, 2022 USD ($) shares	Jan. 31, 2020 installment	Mar. 31, 2023 USD ($) shares	Mar. 31, 2022 USD ($) shares	Dec. 31, 2022 shares	Dec. 31, 2021 shares
Share-based Compensation Arrangement by Share-based Payment Award
Fair value of shares vested | $				$ 181,032	$ 10,667
Inducement Plan
Share-based Compensation Arrangement by Share-based Payment Award
Period from date of termination that any vested options shall expire			90 days
Expiration period			10 years
Unrecognized compensation expense related to unvested options | $				$ 1,935,838
Period for unrecognized compensation expense related to unvested options yet has not been recognized				2 years 10 months 24 days
Aggregate intrinsic value | $				$ 149,000
Stock options granted				250,000
Options exercised				0	0
Inducement Plan | Upon first anniversary of start date
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage			25.00%
Inducement Plan | Each month after the first anniversary
Share-based Compensation Arrangement by Share-based Payment Award
Number of monthly installments | installment			36
2013 Equity Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award
Period from date of termination that any vested options shall expire	90 days
Expiration period	10 years
Common stock authorized					9,506,767
Intrinsic value of options exercised | $				$ 23,760
Cash proceeds from exercise of stock options | $				$ 33,768
Period for unrecognized compensation expense related to unvested options yet has not been recognized				3 years 2 months 12 days
Increase in number of shares of common stock					2,619,622
Shares available for future grants					1,345,998
Aggregate intrinsic value | $				$ 336,000
Stock options granted				2,206,050
Fair value of shares vested | $				$ 704,311	$ 1,263,094
Options exercised				16,800	0
2013 Equity Incentive Plan | Stock options vesting based on performance
Share-based Compensation Arrangement by Share-based Payment Award
Maximum fair value of option excluded from the unrecognized compensation expense | $				$ 825,353
2013 Equity Incentive Plan | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Stock options granted		141,900
Maximum fair value of option excluded from the unrecognized compensation expense | $		$ 113,520
2013 Equity Incentive Plan | Stock options vesting based on performance | Newly hired employees
Share-based Compensation Arrangement by Share-based Payment Award
Stock options granted						584,200	584,200
2013 Equity Incentive Plan | Upon first anniversary of start date
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage	25.00%
2013 Equity Incentive Plan | Each month after the first anniversary
Share-based Compensation Arrangement by Share-based Payment Award
Number of monthly installments | installment	36
2013 Equity Incentive Plan | Vesting upon FDA Approval | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage		50.00%
2013 Equity Incentive Plan | Vesting upon First Commercial Sale | Stock options vesting based on performance | Employees
Share-based Compensation Arrangement by Share-based Payment Award
Vesting percentage		50.00%
Common Stock | Inducement Plan
Share-based Compensation Arrangement by Share-based Payment Award
Increase in number of shares of common stock		3,000,000
Shares available for future grants				409,508
Common Stock | 2013 Equity Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award
Common stock authorized	1,000,000			11,681,878
Shares available for future grants				2,206,376

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