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Statements of Stockholders' Equity - USD ($) | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Total
--- | --- | --- | --- | ---
Balance at Dec. 31, 2021 | $ 52,314 | $ 454,448,327 | $ (372,896,990) | $ 81,603,651
Balance, shares at Dec. 31, 2021 | 52,313,894 |  |  |
Common stock issued under stock plans | $ 78 | (78) |  |
Common stock issued under stock plans, shares | 78,550 |  |  |
Stock-based compensation |  | 1,080,642 |  | 1,080,642
Net loss |  |  | (14,653,041) | (14,653,041)
Balance at Mar. 31, 2022 | $ 52,392 | 455,528,891 | (387,550,031) | 68,031,252
Balance, shares at Mar. 31, 2022 | 52,392,444 |  |  |
Balance at Dec. 31, 2021 | $ 52,314 | 454,448,327 | (372,896,990) | 81,603,651
Balance, shares at Dec. 31, 2021 | 52,313,894 |  |  |
Balance at Dec. 31, 2022 | $ 54,378 | 462,461,251 | (419,585,792) | 42,929,837
Balance, shares at Dec. 31, 2022 | 54,377,798 |  |  |
Balance at Mar. 31, 2022 | $ 52,392 | 455,528,891 | (387,550,031) | 68,031,252
Balance, shares at Mar. 31, 2022 | 52,392,444 |  |  |
Common stock issued under stock plans | $ 32 | (32) |  |
Common stock issued under stock plans, shares | 31,500 |  |  |
Stock-based compensation |  | 963,758 |  | 963,758
Net loss |  |  | (13,267,567) | (13,267,567)
Balance at Jun. 30, 2022 | $ 52,424 | 456,492,617 | (400,817,598) | 55,727,443
Balance, shares at Jun. 30, 2022 | 52,423,944 |  |  |
Balance at Dec. 31, 2022 | $ 54,378 | 462,461,251 | (419,585,792) | 42,929,837
Balance, shares at Dec. 31, 2022 | 54,377,798 |  |  |
Issuance of common stock, net of issuance costs | $ 9,823 | 28,697,188 |  | 28,707,011
Issuance of common stock, net of issuance costs, shares | 9,822,930 |  |  |
Common stock issued under stock plans | $ 44 | 33,724 |  | 33,768
Common stock issued under stock plans, shares | 44,496 |  |  |
Stock-based compensation |  | 870,180 |  | 870,180
Net loss |  |  | (10,359,350) | (10,359,350)
Balance at Mar. 31, 2023 | $ 64,245 | 492,062,343 | (429,945,142) | 62,181,446
Balance, shares at Mar. 31, 2023 | 64,245,224 |  |  |
Common stock issued under stock plans | $ 68 | 20,046 |  | 20,114
Common stock issued under stock plans, shares | 68,109 |  |  |
Stock-based compensation |  | 858,088 |  | 858,088
Net loss |  |  | (8,258,912) | (8,258,912)
Balance at Jun. 30, 2023 | $ 64,313 | $ 492,940,477 | $ (438,204,054) | $ 54,800,736
Balance, shares at Jun. 30, 2023 | 64,313,333 |  |  |

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