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v3.25.3

Segment Reporting - Segment Loss, Including Significant Segment Expenses (Details) - USD ($) $ in Thousands |  | 3 Months Ended | 9 Months Ended
--- | --- | --- | ---
Sep. 30, 2024 | Sep. 30, 2025 | Jun. 30, 2025 | Mar. 31, 2025 | Sep. 30, 2025
Segment Reporting Information [Line Items] |  |  |  |  |  |
Research and development expense | [1] | $ 2,473 | $ 20,347 |  |  | $ 43,059
General and administrative personnel costs | [2] | 158 | 5,538 |  |  | 18,081
Net loss and comprehensive loss |  | (2,631) | (24,607) |  |  | (61,545)
Net loss |  | (2,631) | (24,607) | $ (21,790) | $ (15,148) | (61,545)
Reportable Segment |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
General and administrative personnel costs |  | 112 | 3,225 |  |  | 10,517
Professional and consulting fees |  | 50 | 1,542 |  |  | 5,852
Other segment items |  | 0 | (147) |  |  | 2,545
Net loss and comprehensive loss |  | 2,631 | 24,607 |  |  | 61,545
Net loss |  | 2,631 | 24,607 |  |  | 61,545
Reportable Segment | CR-001 external research and development costs |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Research and development expense |  | 2,469 | 8,714 |  |  | 19,411
Reportable Segment | CR-002 external research and development costs |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Research and development expense |  | 0 | 6,705 |  |  | 11,685
Reportable Segment | Other external research and discovery costs |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Research and development expense |  | 0 | 357 |  |  | 2,179
Reportable Segment | Research and development personnel costs |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |
Research and development expense |  | $ 0 | $ 4,211 |  |  | $ 9,356
[1] | Includes related party amount of $6,175 and $21,244 for the three and nine months ended September 30, 2025, respectively, and $2,473 for the period from September 19, 2024 (inception) through September 30, 2024.
[2] | Includes related party amount of $89 and $719 for the three and nine months ended September 30, 2025, respectively, and $90 for the period from September 19, 2024 (inception) through September 30, 2024.

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