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Segment Reporting | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Segment Reporting | 16. Segment Reporting The Company has one reportable segment relating to the research and development of its research programs, CR-001, CR-002, and CR-003. The Company’s CODM, its Chief Executive Officer, manages the Company’s operations on a company-wide basis for the allocation of resources and the assessment of performance. The Company’s measure of segment profit or loss used to assess performance and allocate resources is net loss and comprehensive loss. Although the Company’s financial reporting package that is reviewed and approved by the CODM disaggregates significant expenses such as program-level external research and development costs, personnel costs, including share-based compensation expense, and professional and consulting fees, all decisions made by the CODM are based upon reviewing operating metrics and performance indications at the Company-wide level. The CODM uses net loss to evaluate loss generated from the Company’s business activities in deciding how to allocate company resources and monitoring budget versus actual results. Assets are also managed on a Company-wide basis. The table below is a summary of the segment loss, including significant segment expenses (in thousands):
| Three Months Ended September 30, 2025 |  | Nine Months Ended September 30, 2025 |  | Period from September 19, 2024 (Inception) Through September 30, 2024
CR-001 external research and development costs | $ | 8,714 |  |  | $ | 19,411 |  |  | $ | 2,469 |
CR-002 external research and development costs | 6,705 |  |  | 11,685 |  |  | — |
Other external research and discovery costs(1) | 357 |  |  | 2,179 |  |  | — |
General and administrative personnel costs | 3,225 |  |  | 10,517 |  |  | 112 |
Research and development personnel costs | 4,211 |  |  | 9,356 |  |  | — |
Professional and consulting fees | 1,542 |  |  | 5,852 |  |  | 50 |
Other segment items (2) | (147) |  |  | 2,545 |  |  | — |
Net loss and comprehensive loss | $ | 24,607 |  |  | $ | 61,545 |  |  | $ | 2,631 |
_________________________ (1)External research and discovery costs include CR-003 costs and other costs associated with candidate discovery activities. (2)Other segment items includes office and facilities expense, interest expense, and miscellaneous other expense offset by interest income.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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