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CONDENSED CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED SHARES AND SHAREHOLDERS' EQUITY (DEFICIT) (UNAUDITED) - USD ($)
$ in Thousands
Total
Reverse Recapitalization Of GlycoMimetics
Series A Non-Voting Preferred Shares
Convertible Notes Payable
Convertible Preferred Stock
Series A Non-Voting Preferred Shares
Series A Non-Voting Preferred Shares
Series A Non-Voting Preferred Shares
Common Stock/Ordinary Shares
Common Stock/Ordinary Shares
Reverse Recapitalization Of GlycoMimetics
 [2]
Common Stock/Ordinary Shares
Convertible Notes Payable
 [2]
Additional Paid-in Capital
Additional Paid-in Capital
Reverse Recapitalization Of GlycoMimetics
Additional Paid-in Capital
Convertible Notes Payable
Accumulated Deficit
Beginning balance, Convertible Preferred Stock (in shares) at Sep. 19, 2024         0                  
Beginning balance, Convertible Preferred Stock at Sep. 19, 2024         $ 0                  
Increase (Decrease) in Temporary Equity [Roll Forward]                            
Issuance of Series Seed convertible preferred stock (in shares)         20,000,000                  
Issuance of Series Seed convertible preferred stock         $ 4,000                  
Ending balance, Convertible Preferred Stock (in shares) at Sep. 30, 2024         20,000,000                  
Ending balance, Convertible Preferred Stock at Sep. 30, 2024         $ 4,000                  
Beginning balance (in shares) at Sep. 19, 2024           0                
Beginning balance at Sep. 19, 2024 $ 0         $ 0   $ 0 [1]     $ 0     $ 0
Beginning balance (in shares) at Sep. 19, 2024 [1]               0            
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Issuance of common stock (in shares) [1]               959,384            
Issuance of common stock 1,260             $ 1 [1]     1,259      
Stock-based compensation expense 69                   69      
Net loss (2,631)                         (2,631)
Ending balance (in shares) at Sep. 30, 2024           0                
Ending balance at Sep. 30, 2024 (1,302)         $ 0   $ 1 [1]     1,328     (2,631)
Ending balance (in shares) at Sep. 30, 2024 [1]               959,384            
Beginning balance, Convertible Preferred Stock (in shares) at Dec. 31, 2024         20,000,000                  
Beginning balance, Convertible Preferred Stock at Dec. 31, 2024         $ 4,000                  
Ending balance, Convertible Preferred Stock (in shares) at Mar. 31, 2025         20,000,000                  
Ending balance, Convertible Preferred Stock at Mar. 31, 2025         $ 4,000                  
Beginning balance (in shares) at Dec. 31, 2024     0     0                
Beginning balance at Dec. 31, 2024 $ (15,479)         $ 0   $ 1 [2]     2,387     (17,867)
Beginning balance (in shares) at Dec. 31, 2024 1,018,604             1,018,604 [2]            
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Stock-based compensation expense $ 466                   466      
Early exercise of stock options (in shares) [2]               811            
Net loss (15,148)                         (15,148)
Ending balance (in shares) at Mar. 31, 2025           0                
Ending balance at Mar. 31, 2025 (30,161)         $ 0   $ 1 [2]     2,853     (33,015)
Ending balance (in shares) at Mar. 31, 2025 [2]               1,019,415            
Beginning balance, Convertible Preferred Stock (in shares) at Dec. 31, 2024         20,000,000                  
Beginning balance, Convertible Preferred Stock at Dec. 31, 2024         $ 4,000                  
Ending balance, Convertible Preferred Stock (in shares) at Sep. 30, 2025         0                  
Ending balance, Convertible Preferred Stock at Sep. 30, 2025         $ 0                  
Beginning balance (in shares) at Dec. 31, 2024     0     0                
Beginning balance at Dec. 31, 2024 $ (15,479)         $ 0   $ 1 [2]     2,387     (17,867)
Beginning balance (in shares) at Dec. 31, 2024 1,018,604             1,018,604 [2]            
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Early exercise of stock options (in shares) 811                          
Net loss $ (61,545)                          
Ending balance (in shares) at Sep. 30, 2025     2,890     2,890                
Ending balance at Sep. 30, 2025 $ 116,641         $ 4,000   $ 14 [2]     192,039     (79,412)
Ending balance (in shares) at Sep. 30, 2025 13,892,516             13,892,516 [2]            
Beginning balance, Convertible Preferred Stock (in shares) at Mar. 31, 2025         20,000,000                  
Beginning balance, Convertible Preferred Stock at Mar. 31, 2025         $ 4,000                  
Increase (Decrease) in Temporary Equity [Roll Forward]                            
Exchange of Series Seed convertible preferred stock for Series A non-voting convertible preferred shares upon the closing of the reverse recapitalization (in shares)         (20,000,000)                  
Exchange of Series Seed convertible preferred stock for Series A non-voting convertible preferred shares upon the closing of the reverse recapitalization         $ (4,000)                  
Ending balance, Convertible Preferred Stock (in shares) at Jun. 30, 2025         0                  
Ending balance, Convertible Preferred Stock at Jun. 30, 2025         $ 0                  
Beginning balance (in shares) at Mar. 31, 2025           0                
Beginning balance at Mar. 31, 2025 $ (30,161)         $ 0   $ 1 [2]     2,853     (33,015)
Beginning balance (in shares) at Mar. 31, 2025 [2]               1,019,415            
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Repurchase and cancellation of restricted stock awards (in shares) [2]               (127,889)            
Repurchase and cancellation of restricted stock awards (177)                   (177)      
Conversion of convertible securities (in shares)             2,890   645,274 1,850,790        
Conversion of convertible securities   $ 525 $ 4,000 $ 40,515     $ 4,000     $ 2   $ 525 $ 40,513  
Issuance of common stock and pre-funded warrants in the Pre-Closing financing (in shares) [2]               10,504,926            
Issuance of ordinary shares and pre-funded warrants in the Pre-Closing financing 159,475             $ 11 [2]     159,464      
Issuance costs of Pre-closing financing and reverse recapitalization (17,201)                   (17,201)      
Stock-based compensation expense 4,068                   4,068      
Net loss (21,790)                         (21,790)
Ending balance (in shares) at Jun. 30, 2025           2,890                
Ending balance at Jun. 30, 2025 139,254         $ 4,000   $ 14 [2]     190,045     (54,805)
Ending balance (in shares) at Jun. 30, 2025 [2]               13,892,516            
Ending balance, Convertible Preferred Stock (in shares) at Sep. 30, 2025         0                  
Ending balance, Convertible Preferred Stock at Sep. 30, 2025         $ 0                  
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Stock-based compensation expense 1,994                   1,994      
Net loss (24,607)                         (24,607)
Ending balance (in shares) at Sep. 30, 2025     2,890     2,890                
Ending balance at Sep. 30, 2025 $ 116,641         $ 4,000   $ 14 [2]     $ 192,039     $ (79,412)
Ending balance (in shares) at Sep. 30, 2025 13,892,516             13,892,516 [2]            
[1] Includes issuance of 236,884 restricted stock awards (see Note 9)
[2] Includes issuance of 296,104 restricted stock awards (see Note 9)