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Segment Reporting - Segment Loss, Including Significant Segment Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Dec. 31, 2024
Sep. 30, 2025
Segment Reporting Information [Line Items]            
Research and development expense $ 2,473 [1] $ 20,347 [1]     $ 14,034 [2] $ 43,059 [1]
General and administrative personnel costs 158 [3] 5,538 [3]     3,157 [4] 18,081 [3]
Net loss and comprehensive loss (2,631) (24,607)     (17,867) (61,545)
Net loss (2,631) (24,607) $ (21,790) $ (15,148) (17,867) (61,545)
Reportable Segment            
Segment Reporting Information [Line Items]            
General and administrative personnel costs 112 3,225     1,153 10,517
Professional and consulting fees 50 1,542     1,981 5,852
Other segment items 0 (147)     911 2,545
Net loss and comprehensive loss 2,631 24,607     17,867 61,545
Net loss 2,631 24,607     17,867 61,545
Reportable Segment | CR-001 external research and development costs            
Segment Reporting Information [Line Items]            
Research and development expense 2,469 8,714     10,510 19,411
Reportable Segment | CR-002 external research and development costs            
Segment Reporting Information [Line Items]            
Research and development expense 0 6,705     3,251 11,685
Reportable Segment | Other external research and discovery costs            
Segment Reporting Information [Line Items]            
Research and development expense 0 357       2,179
Reportable Segment | Research and development personnel costs            
Segment Reporting Information [Line Items]            
Research and development expense $ 0 $ 4,211     $ 61 $ 9,356
[1] Includes related party amount of $6,175 and $21,244 for the three and nine months ended September 30, 2025, respectively, and $2,473 for the period from September 19, 2024 (inception) through September 30, 2024.
[2] Includes related party amount of $13,185 for the period from September 19, 2024 (inception) to December 31, 2024 (see Note 12).
[3] Includes related party amount of $89 and $719 for the three and nine months ended September 30, 2025, respectively, and $90 for the period from September 19, 2024 (inception) through September 30, 2024.
[4] Includes related party amount of $571 for the period from September 19, 2024 (inception) to December 31, 2024 (see Note 12).