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Segment Reporting (Tables) | 12 Months Ended
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Dec. 31, 2025
Segment Reporting [Abstract] |
Schedule of segment loss, including significant segment expenses | The table below is a summary of the segment loss, including significant segment expenses (in thousands):
| Twelve Months Ended December 31, 2025 |  | Period from September 19, 2024 (Inception) Through December 31, 2024
License revenue | $ | 10,844 |  |  | $ | — |
Less: |  |  |
CR-001 external research and development costs | 25,547 |  |  | 6,610 |
CR-002 external research and development costs | 8,636 |  |  | 751 |
Discovery external research and development costs(1) | 1,952 |  |  | — |
Personnel costs | 31,022 |  |  | 1,214 |
Milestone and license fees(2) | 84,710 |  |  | 6,400 |
Professional and other fees(3) | 11,609 |  |  | 2,216 |
Other expense (income) | (690) |  |  | 676 |
Provision for income taxes | 2,000 |  |  | — |
Net loss and comprehensive loss | $ | (153,942) |  |  | $ | (17,867) |
_________________________ (1)Discovery external research and discovery costs include costs associated with candidate discovery activities. (2)Milestone and license fees for the twelve months ended December 31, 2025 includes the license fee for CR-003 related to the SKB105 License Agreement. (3)Profession and other fees includes professional fees, consulting fees, office and facilities expense, and miscellaneous other expense.

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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