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Summary of Significant Accounting Policies - Revenue Recognition - Condensed Statement of Operations (Details) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017
Summary of Significant Accounting Policies |  |  |  |
Total revenue | $ 10,765 |  | $ 25,618 |
Total cost of sales | 6,229 |  | 11,127 |
Gross profit | 4,536 | $ 5,792 | 14,491 | $ 10,009
Loss from operations | (7,279) | (4,789) | (8,389) | (10,664)
Net loss and comprehensive loss | $ (7,369) | $ (5,187) | $ (8,646) | $ (11,273)
Net loss per common share, basic and diluted | $ (0.44) | $ (0.42) | $ (0.55) | $ (0.91)
Product sales |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | $ 9,449 |  | $ 18,814 |
Licensing, royalty and other revenue |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | 1,316 |  | 6,804 |
ASU 2014-09 | Balances without the adoption of Topic 606 |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | 10,053 |  | 24,103 |
Total cost of sales | 6,336 |  | 10,940 |
Gross profit | 3,717 |  | 13,163 |
Loss from operations | (8,098) |  | (9,717) |
Net loss and comprehensive loss | $ (8,188) |  | $ (9,974) |
Net loss per common share, basic and diluted | $ (0.49) |  | $ (0.63) |
ASU 2014-09 | Adjustments |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | $ (712) |  | $ (1,515) |
Total cost of sales | 107 |  | (187) |
Gross profit | (819) |  | (1,328) |
Loss from operations | (819) |  | (1,328) |
Net loss and comprehensive loss | $ (819) |  | $ (1,328) |
Net loss per common share, basic and diluted | $ (0.05) |  | $ (0.08) |
ASU 2014-09 | Product sales | Balances without the adoption of Topic 606 |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | $ 8,863 |  | $ 17,396 |
ASU 2014-09 | Product sales | Adjustments |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | (586) |  | (1,418) |
ASU 2014-09 | Licensing, royalty and other revenue | Balances without the adoption of Topic 606 |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | 1,190 |  | 6,707 |
ASU 2014-09 | Licensing, royalty and other revenue | Adjustments |  |  |  |
Summary of Significant Accounting Policies |  |  |  |
Total revenue | $ (126) |  | $ (97) |

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