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Leases (Details)
$ in Thousands
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Dec. 31, 2017
ft²
Dec. 31, 2018
USD ($)
Leases            
Operating lease, option to extend         true  
Operating lease, option to terminate         true  
Future operating lease payments            
2019 (remaining three months) $ 430   $ 430      
2020 1,736   1,736      
2021 859   859      
2022 50   50      
Total undiscounted lease payments 3,075   3,075      
Less: Present value adjustment (162)   (162)      
Total operating lease liabilities 2,913   2,913      
Less: Current portion of operating lease liabilities (1,606)   (1,606)      
Total operating lease liabilities, net of current portion $ 1,307   $ 1,307      
Minimum rental commitments            
2019           $ 1,645
2020           1,701
2021           846
2022           47
Total minimum lease payments           $ 4,239
Other lease information            
Operating lease weighted-average remaining lease term (years) 1 year 10 months 21 days   1 year 10 months 21 days      
Operating lease weighted-average discount rate 6.01%   6.01%      
Operating lease costs $ 401 $ 386 $ 1,200 $ 1,200    
Previous Headquarters            
Leases            
Area of operating lease (in sq feet) | ft²         27,974  
Office and Lab Space            
Leases            
Operating lease renewal term (in years) 5 years   5 years      
Arizona manufacturing facility            
Leases            
Period to cancel lease upon notice     24 months