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Stock-Based Compensation (Details) - Employee And Nonemployee Stock Option And Restricted Stock Units [Member] - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Employee Service Share Based Compensation Allocation Of Recognized Period Costs        
Stock-based compensation expense $ 12,282 $ 11,939 $ 39,011 $ 40,418
Stock-based compensation expense capitalized into inventory 290 241 904 758
Cost of Goods Sold        
Employee Service Share Based Compensation Allocation Of Recognized Period Costs        
Stock-based compensation expense 184 394 555 896
Research and Development Expense        
Employee Service Share Based Compensation Allocation Of Recognized Period Costs        
Stock-based compensation expense 5,173 4,126 14,707 14,642
Selling, General and Administrative Expenses        
Employee Service Share Based Compensation Allocation Of Recognized Period Costs        
Stock-based compensation expense $ 6,925 $ 7,419 $ 23,749 $ 24,880