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Inventory - Additional Information (Details) - USD ($)
 3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Mar. 31, 2021
Sep. 30, 2022
Dec. 31, 2021
Sep. 30, 2021
Inventory [Line Items]            
Write-downs of inventory $ 26,000,000.0 $ 5,200,000   $ 26,000,000   $ 5,192,000
Estimate increased the net loss, amount $ 26,000,000.0     $ 26,000,000.0    
Estimated net loss per share (basic and diluted) $ 0.33     $ 0.34    
Inventory reserves $ 26,000,000.0     $ 26,000,000.0 $ 200,000  
Prepayment made for manufacturing services 20,633,000     20,633,000 13,666,000  
Other assets, non-current 9,627,000     9,627,000 10,025,000  
Inventory 27,719,000     27,719,000 37,642,000  
Impairment charge within research and development expenses     $ 3,200,000 0 0 3,210,000
Research and development 45,808,000 $ 54,085,000   170,336,000   $ 312,343,000
Prepayments made to a CMO for manufacturing services for UDENYCA 16,600,000     16,600,000 8,300,000  
Prepayments made to a CMO For Other Research And Development Pipeline Program 4,000,000.0     4,000,000.0 $ 5,400,000  
Yusimry Product [Member]            
Inventory [Line Items]            
Inventory $ 24,600,000     $ 24,600,000    
CHS-2020            
Inventory [Line Items]            
Research and development     $ 11,500,000