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Debt Obligations - 2027 Term Loan - Narrative (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Mar. 31, 2022 USD ($) | Jan. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Sep. 14, 2022 USD ($) | Jan. 05, 2022 USD ($) tranche | Apr. 30, 2020 USD ($) | Feb. 29, 2016 USD ($)
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Outstanding amount paid off |  |  |  | $ 81,750 |  |  |  |
Outstanding amount payoff |  |  |  | $ 109,000 |  |  |  |
2027 Term Loans |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Debt Instrument, Interest Rate During Period |  |  | 12.00% |  |  |  |  |
2027 Term Loans | Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member] |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Spread on variable rate |  |  |  | 1.00% |  |  |  |
Debt Instrument, Interest Rate During Period |  |  |  | 0.26161% |  |  |  |
2027 Term Loans | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  |  | $ 300,000 |  |
Number of tranches | tranche |  |  |  |  |  | 4 |  |
Net carrying value |  |  | $ 245,483 | $ 245,483 |  |  |  |
Loan agreement covenants, minimum trailing twelve month net sales for current quarter |  | $ 200,000 |  |  |  |  |  |
Loan agreement covenants, minimum trailing twelve month net sales for the quarter ended March 30, 2024 |  | 210,000 |  |  |  |  |  |
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended June 30, 2024 |  | 230,000 |  |  |  |  |  |
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended September 30, 2024 |  | 270,000 |  |  |  |  |  |
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended December 31, 2024 and thereafter |  | $ 300,000 |  |  |  |  |  |
Mandatory prepayment term |  | 10 days |  |  |  |  |  |
Debt discounts and issuance costs |  | $ 6,800 |  |  |  |  |  |
Remaining unamortized debt discount and debt offering costs |  |  | $ 4,517 | $ 4,517 |  |  |  |
2027 Term Loans | BioPharma Credit Investments V GP LLC | Three-month LIBOR |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Spread on variable rate |  | 1.00% |  |  |  |  |  |
2027 Term Loans | Additional facility amount | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Uncommitted additional facility |  | $ 100,000 |  |  |  |  |  |
2027 Term Loans | Through March 31, 2023 | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Stated interest rate |  | 8.25% |  |  |  |  |  |
2027 Term Loans | Starting April 1, 2023 |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Stated interest rate |  |  | 8.25% | 8.25% |  |  |  |
Tranche A Loan, funded January 5, 2022 | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  |  | $ 100,000 |  |
Debt discounts and issuance costs |  | $ 7,800 |  |  |  |  |  |
Tranche B Loan, funded no later than April 1, 2022 | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount | $ 100,000 |  |  |  |  |  |  |
Debt discounts and issuance costs | 2,300 |  |  |  |  |  |  |
Convertible notes, Issuance Cost | 1,000 |  |  |  |  |  |  |
Tranche C Loan, funded between April 1, 2022 and March 17, 2023 | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Amount not funded |  | 50,000 |  |  |  |  |  |
Tranche D Loan, funded on September 14, 2022 | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  | $ 50,000 |  |  |
Convertible notes, Issuance Cost |  |  |  |  | $ 500 |  |  |
1.5% Convertible Senior Subordinated Notes due 2026 | Convertible Notes |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  |  |  | $ 230,000 |
Net carrying value |  |  | $ 225,575 | $ 225,575 |  |  |  |
Stated interest rate |  |  |  |  |  |  | 1.50% |
Remaining unamortized debt discount and debt offering costs |  |  | $ 4,425 | $ 4,425 |  |  |  |
Total term of the loan |  |  |  | 3 years 3 months 18 days |  |  |  |
Effective interest rate |  |  | 2.10% | 2.10% |  |  |  |
1.5% Convertible Senior Subordinated Notes due 2026 | BioPharma Credit Investments V GP LLC | Scenario, Plan | Maximum |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount |  | 50,000 |  |  |  |  |  |
8.2% Convertible Notes due 2022 | Convertible Notes |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  |  |  |  | $ 100,000
Stated interest rate |  |  |  |  |  |  |  | 8.20%
Outstanding amount payoff | $ 111,100 |  |  |  |  |  |  |
Convertible notes, Issuance Cost |  |  |  |  |  |  |  | $ 800
2025 Term Loan |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Net carrying value |  |  | $ 0 | $ 0 |  |  |  |
2025 Term Loan | Convertible Notes |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Outstanding amount paid off |  | $ 81,900 |  |  |  |  |  |
Tranche A and B Loans | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Remaining unamortized debt discount and debt offering costs |  |  | $ 4,500 | $ 4,500 |  |  |  |
Tranches A, B and D | BioPharma Credit Investments V GP LLC |  |  |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |  |  |
Remaining term |  |  |  | 4 years |  |  |  |

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