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Balance Sheet Components
12 Months Ended
Dec. 31, 2022
Balance Sheet Components  
Balance Sheet Components

5.Balance Sheet Components

Property and Equipment, Net

Property and equipment, net consisted of the following:

    

December 31, 

(in thousands)

2022

2021

Machinery and equipment

$

12,944

$

11,876

Computer equipment and software

 

3,183

 

3,033

Furniture and fixtures

 

1,258

 

1,129

Leasehold improvements

 

6,198

 

5,942

Finance lease right of use assets

4,632

2,294

Construction in progress

 

696

 

388

Total property and equipment

 

28,911

 

24,662

Accumulated depreciation and amortization

 

(20,157)

 

(16,849)

Property and equipment, net

$

8,754

$

7,813

Depreciation and amortization expense related to property and equipment, net was $3.6 million, $3.5 million, and $2.9 million in 2022, 2021 and 2020, respectively. There were no material impairments of property and equipment in 2022, 2021 and 2020.

As of December 31, 2022 and 2021, the net book value of software implementation costs related to hosting arrangements was $3.5 million and $1.3 million, respectively, and the amortization expense was immaterial for all periods presented.

Accrued and Other Current Liabilities

Accrued and other current liabilities consisted of the following:

    

December 31, 

(in thousands)

2022

2021

Accrued commercial and research and development manufacturing

$

21,774

$

30,541

Accrued co-development costs payable to Junshi Biosciences

8,356

1,926

Lease liabilities, current

4,318

3,492

Accrued other

 

15,649

 

12,168

Total Accrued and other current liabilities

$

50,097

$

48,127